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HIGH YIELD > Drugs I've Never Heard Of > Flashcards

Drugs I've Never Heard Of Flashcards

1
Q

Milnacipran

Levomilnacipran

A

SNRI’s

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2
Q

Doxepin

A

TCA

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3
Q

Amoxapine

A

TCA

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4
Q

Tranylcypromine

A

MAO

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5
Q

Vilazodone

A

Inhibit 5-HT reuptake - 5-HT1a partial agonist
Used for MDD and GAD

Headaches, Diarrhea, Nausea, Weight Gain
Anti-cholinergic effects

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6
Q

Vortioxetine

A

5-HT1a agonist
5-HT3 antagonist

Used for MDD
Nausea, Sexual dysfunction, WEIRD DREAMS
Anti-cholinergic effects

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7
Q

Chlordiazepoxide

A

Benzodiazepene

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8
Q

Primidone

A

Barbiturate

Used for Essential Tremor

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9
Q

Tigabine

A

Increases GABA by inhibiting reuptake

Used for Tonic Clonic seizures

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10
Q

Vigabatrin

A

Increases GABA by irreversibly inhibiting GABA transaminase

Used for Tonic Clonic seizures

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11
Q

Suvorexant

A

Orexin (Hypocretin) receptor antagonist
Used for insomnia
Can cause abnormal dreams or URI

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12
Q

Memantine

A

NMDA antagonist

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13
Q

Cyclobenzaprine

A

Centrally acting muscle relaxant

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14
Q

Pentazocine

A

Kappa-Opioid receptor agonist
Mu-Opioid receptor Antagonist

Kappa causes MIOISIS

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15
Q

Butorphanol

A

Kappa-Opioid receptor agonist
Mu-Opioid receptor PARTIAL Agonist

Severe pain (Migraine, Labor)
Causes less respiratory depression than other opioids
Overdose not as easily reversed with Naloxone
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16
Q

Timolol, Betaxolol, Carteolol

A

Decrease aqueous humor synthesis

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17
Q

Pilocarpine, Carbachol

Physostigmine, Echothiophate

A

Increase outflow of aqueous humor via contraction of ciliary muscle and opening of trabecular meshwork

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18
Q

Hydroxychloroquine

A

Anti-rheumatic drug

Irreversible retinopathy and myopathy

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19
Q

Pyridium

A

Uricalm
UTI Analgesic
Causes G6PD

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20
Q

Tizanidine

A

Centrally acting alpha2 agonist

Muscle relaxant

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21
Q

Guanfacine

A

Alpha2 agonist
(Same indications as Clonidine)
Treat: Hypertensive urgency, ADHD, Tourette Syndrome

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22
Q

Bromonidine

A

Alpha2 agonist

Treat: Glaucoma

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23
Q

Ritodrine

A

Beta2 agonist

Tocolytic

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24
Q

Fenoldapam

A

D1 agonist
Treat: Postoperative hypertension
Promotes natriuresis

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25
Q

Midodrine

A

Alpha1 agonist

Treat: Autonomic insufficiency and postural hypotension

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26
Q

Mirabegron

A

Beta3 agonist

Treat: Urinary urge incontinence or overactive bladder

27
Q

Homatropine, Tropicamide

A

Muscarinic antagonist

Produces mydriasis and cycloplegia

28
Q

Glycopyrrolate

A

Muscarinic antagonist
Used: Preoperatively to reduce airway secretions
Treat: Drooling, Peptic ulcer

29
Q

Hyoscyamine, Dicyclomine

A

Muscarinic antagonist

Treat: Anti-spasmodic for IBS

30
Q

Solifenacin

A

Muscarinic antagonist

Reduce bladder spasms and urge incontinence

31
Q

Atomoxetine

A

NE Transporter inhibitor
Promote release of Norepi into synapse
Treat: ADHD

32
Q

Alirocumab, Evolocumab

A

PCSK9 Inhibitors

Inactive LDL-receptor degradation, increasing LDL absorbed form bloodstream

33
Q

Pimozide

A

1st Gen Antipsychotic

34
Q

Asenapine

A

2nd Gen Antipsychotic

35
Q

Iloperidone

A

2nd Gen Antipsychotic

36
Q

Paliperidone

A

2nd Gen Antipsychotic

37
Q

Aripiprazole

A

2nd Gen Antipsychotic

D2 Partial Agonist

38
Q

Tocilizumab

A

Antibody against IL-6

Effective in treating Giant Cell Arteritis

39
Q

Cilostazol, Dipyridamole

A

PDE Inhibitors
Increase cAMP in platelets
Inhibition of platelet aggregation
Vasodilators

40
Q

Ticlopidine

A 
Block ADP (P2Y12) receptor
Prevent expression of GpIIb/IIIa

Also: Clopidogrel, Prasugrel, Ticagrelor (reversible)

41
Q

Abciximab

A

GpIIb/IIIa inhibitor

Made from monoclonal Fab fragments

42
Q

Eptifibatide, Tirofiban

A

GpIIb/IIIa inhibitor

43
Q

Iquimod

A

IMP nucleoside analog that acts as an agonist of Toll-Like Receptor 7 and 8 which leads to activation of NF-kB

Used as an immunomodulator in the treatment of genital or perianal warts/condyloma and actinic keratosis

44
Q

Alemtuzumab

A

Anti-CD52 - inhibits B and T Cells (Mature lymphocytes)

Used for CLL

45
Q

Sunitinib/Sorafenib

A

VEGFR inhibitors
Used for Renal Cell Carcinoma

SE: Hyperkeratosis, Rashes, Increased risk of hemorrhage

46
Q

Erlotinib

A

EGFR Tyrosine Kinase Inhibitor
NSCLC

SE: Rash, Acneiform eruption, Diarrhea

47
Q

Cetuximab

A

Monoclonal antibody against EGFR
Used for Stage IV Colorectal cancer (KRAS), Squamous Cell Carcinoma

SEL Rash, Elevated LFTs, Diarrhea, Infusion reaction

48
Q

Bortezomib, Carfilzomib

A

Proteasome inhibitors - induce arrest at G2-M phase
Used for Multiple Myeloma, Mantle Cell Lymphoma

SE: Peripheral neuropathy, VZV

49
Q

Vemurafenib

A

V600E-BRAF

Used for Metastatic Melanoma

50
Q

Exemestane

A

Aromatase inhibitor

Can be used for ER+ breast cancer in POST-menopausal women
Anastrazole. Letrozole

51
Q

Xylometazoline, Oxymetazoline

A

Nasal decongestants (Spray)

52
Q

Aprepitant, Fosaprepitant

A

Neurokinin 1 antagonsits
Anti-Nausea
Prevent Substance P release

53
Q

Phytomenadione
Phylloquinone
Phytonadione

54
Q

Nesiritide

A

BNP analog

55
Q

Sacubitril

A

Neprilysin inhibitors - prevent the degradation of BNP

56
Q

Regadenoson

A

Vasodilator for coronary steal syndrome

57
Q

Diclofenac

58
Q

Ketorolac

59
Q

Meloxicam

60
Q

Piroxicam

61
Q

Fludrocortisone

A

Synthetic analog of Aldosterone

62
Q

Cetirizine

A

Second Gen H1 (Gq) antihistamine

Less anti-muscarinic effects

63
Q

Epoprostenol, Iloprost

A

PGI2 agonists

Vasodilate pulmonary and arterial vessels in Pulmonary HTN

64
Q

Dipyridamole, Regadenoson

A

Vasodilators used in Coronary Steal Syndrome (p.293)

HIGH YIELD (21 decks)

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