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HIGH YIELD > Drugs I've Never Heard Of > Flashcards

Drugs I've Never Heard Of Flashcards

1
Q

Milnacipran

Levomilnacipran

A

SNRI’s

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2
Q

Doxepin

A

TCA

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3
Q

Amoxapine

A

TCA

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4
Q

Tranylcypromine

A

MAO

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5
Q

Vilazodone

A

Inhibit 5-HT reuptake - 5-HT1a partial agonist
Used for MDD and GAD

Headaches, Diarrhea, Nausea, Weight Gain
Anti-cholinergic effects

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6
Q

Vortioxetine

A

5-HT1a agonist
5-HT3 antagonist

Used for MDD
Nausea, Sexual dysfunction, WEIRD DREAMS
Anti-cholinergic effects

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7
Q

Chlordiazepoxide

A

Benzodiazepene

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8
Q

Primidone

A

Barbiturate

Used for Essential Tremor

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9
Q

Tigabine

A

Increases GABA by inhibiting reuptake

Used for Tonic Clonic seizures

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10
Q

Vigabatrin

A

Increases GABA by irreversibly inhibiting GABA transaminase

Used for Tonic Clonic seizures

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11
Q

Suvorexant

A

Orexin (Hypocretin) receptor antagonist
Used for insomnia
Can cause abnormal dreams or URI

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12
Q

Memantine

A

NMDA antagonist

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13
Q

Cyclobenzaprine

A

Centrally acting muscle relaxant

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14
Q

Pentazocine

A

Kappa-Opioid receptor agonist
Mu-Opioid receptor Antagonist

Kappa causes MIOISIS

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15
Q

Butorphanol

A

Kappa-Opioid receptor agonist
Mu-Opioid receptor PARTIAL Agonist

Severe pain (Migraine, Labor)
Causes less respiratory depression than other opioids
Overdose not as easily reversed with Naloxone
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16
Q

Timolol, Betaxolol, Carteolol

A

Decrease aqueous humor synthesis

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17
Q

Pilocarpine, Carbachol

Physostigmine, Echothiophate

A

Increase outflow of aqueous humor via contraction of ciliary muscle and opening of trabecular meshwork

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18
Q

Hydroxychloroquine

A

Anti-rheumatic drug

Irreversible retinopathy and myopathy

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19
Q

Pyridium

A

Uricalm
UTI Analgesic
Causes G6PD

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20
Q

Tizanidine

A

Centrally acting alpha2 agonist

Muscle relaxant

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21
Q

Guanfacine

A

Alpha2 agonist
(Same indications as Clonidine)
Treat: Hypertensive urgency, ADHD, Tourette Syndrome

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22
Q

Bromonidine

A

Alpha2 agonist

Treat: Glaucoma

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23
Q

Ritodrine

A

Beta2 agonist

Tocolytic

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24
Q

Fenoldapam

A

D1 agonist
Treat: Postoperative hypertension
Promotes natriuresis

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25
Midodrine
Alpha1 agonist | Treat: Autonomic insufficiency and postural hypotension
26
Mirabegron
Beta3 agonist | Treat: Urinary urge incontinence or overactive bladder
27
Homatropine, Tropicamide
Muscarinic antagonist | Produces mydriasis and cycloplegia
28
Glycopyrrolate
Muscarinic antagonist Used: Preoperatively to reduce airway secretions Treat: Drooling, Peptic ulcer
29
Hyoscyamine, Dicyclomine
Muscarinic antagonist | Treat: Anti-spasmodic for IBS
30
Solifenacin
Muscarinic antagonist | Reduce bladder spasms and urge incontinence
31
Atomoxetine
NE Transporter inhibitor Promote release of Norepi into synapse Treat: ADHD
32
Alirocumab, Evolocumab
PCSK9 Inhibitors | Inactive LDL-receptor degradation, increasing LDL absorbed form bloodstream
33
Pimozide
1st Gen Antipsychotic
34
Asenapine
2nd Gen Antipsychotic
35
Iloperidone
2nd Gen Antipsychotic
36
Paliperidone
2nd Gen Antipsychotic
37
Aripiprazole
2nd Gen Antipsychotic | D2 Partial Agonist
38
Tocilizumab
Antibody against IL-6 | Effective in treating Giant Cell Arteritis
39
Cilostazol, Dipyridamole
PDE Inhibitors Increase cAMP in platelets Inhibition of platelet aggregation Vasodilators
40
Ticlopidine
``` Block ADP (P2Y12) receptor Prevent expression of GpIIb/IIIa ``` Also: Clopidogrel, Prasugrel, Ticagrelor (reversible)
41
Abciximab
GpIIb/IIIa inhibitor | Made from monoclonal Fab fragments
42
Eptifibatide, Tirofiban
GpIIb/IIIa inhibitor
43
Iquimod
IMP nucleoside analog that acts as an agonist of Toll-Like Receptor 7 and 8 which leads to activation of NF-kB Used as an immunomodulator in the treatment of genital or perianal warts/condyloma and actinic keratosis
44
Alemtuzumab
Anti-CD52 - inhibits B and T Cells (Mature lymphocytes) | Used for CLL
45
Sunitinib/Sorafenib
VEGFR inhibitors Used for Renal Cell Carcinoma SE: Hyperkeratosis, Rashes, Increased risk of hemorrhage
46
Erlotinib
EGFR Tyrosine Kinase Inhibitor NSCLC SE: Rash, Acneiform eruption, Diarrhea
47
Cetuximab
Monoclonal antibody against EGFR Used for Stage IV Colorectal cancer (KRAS), Squamous Cell Carcinoma SEL Rash, Elevated LFTs, Diarrhea, Infusion reaction
48
Bortezomib, Carfilzomib
Proteasome inhibitors - induce arrest at G2-M phase Used for Multiple Myeloma, Mantle Cell Lymphoma SE: Peripheral neuropathy, VZV
49
Vemurafenib
V600E-BRAF | Used for Metastatic Melanoma
50
Exemestane
Aromatase inhibitor Can be used for ER+ breast cancer in POST-menopausal women Anastrazole. Letrozole
51
Xylometazoline, Oxymetazoline
Nasal decongestants (Spray)
52
Aprepitant, Fosaprepitant
Neurokinin 1 antagonsits Anti-Nausea Prevent Substance P release
53
Phytomenadione Phylloquinone Phytonadione
Vitamin K
54
Nesiritide
BNP analog
55
Sacubitril
Neprilysin inhibitors - prevent the degradation of BNP
56
Regadenoson
Vasodilator for coronary steal syndrome
57
Diclofenac
NSAID
58
Ketorolac
NSAID
59
Meloxicam
NSAID
60
Piroxicam
NSAID
61
Fludrocortisone
Synthetic analog of Aldosterone
62
Cetirizine
Second Gen H1 (Gq) antihistamine | Less anti-muscarinic effects
63
Epoprostenol, Iloprost
PGI2 agonists | Vasodilate pulmonary and arterial vessels in Pulmonary HTN
64
Dipyridamole, Regadenoson
Vasodilators used in Coronary Steal Syndrome (p.293)

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