1. Vaginitis - Topical azoles 2. Oral/Esophageal - Nystatin, Fluconazole, Caspofungin 3. Systemic - Fluconazole, Caspofungin, Ampho B

Classic/High Yield Treatments (p. 661-664) Flashcards by Talley Cook

Absence seizures

Ethosuxamide

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Acute gout attack

NSAIDs, Colchicine, Glucocorticoids

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Acute promyelocytic leukemia (M3)

All-trans retinoic acid

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ADHD

Methylphenidate
Amphetamines
CBT
Atomoxetine
Guanfacine
Clonidine

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Alcoholism

Disulfiram
Acamprosate
Naltrexone
Supportive care

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Alcohol withdrawal

Long-acting benzodiazepenes

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Anorexia

Nutrition, Psychotherapy

Mirtazapine

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Arrythmia in damaged cardiac tissue

Class IB antiarrythmic (Lidocaine, Mexilitine)

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Benign prostatic hyperplasia

A1-antagonists
5a-reductase inhibitors
PDE-5 inhibitors

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Bipolar disorder

Mood stabilizers - Lithium, Valproic acid, Carbamazepine

Atypical antipsychotics

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Breast cancer in postmenopausal women

Aromatase inhibitor (Anastrozole)

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Buerger disease

Smoking cessation

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Bulimia nervosa

SSRIs

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Candida albicans

Vaginitis - Topical azoles
Oral/Esophageal - Nystatin, Fluconazole, Caspofungin
Systemic - Fluconazole, Caspofungin, Ampho B

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Carcinoid syndrome

Octreotide

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Chlamydia trachomatis

Doxycycline (+ Ceftriaxone for gonorrhea confection

Erythromycin eye drops (Conjunctivitis prophylaxis in infants)

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Chronic Gout

Xantine oxidase inhibitors (Allopurinol, Feboxostat)
Pegloticase
Probenecid

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Chronic Hep B or C

IFN-a (HBV and HCV)

Ribavrin, Simprevir, Sofosbuvir (HCV)

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Chronic myelogenous leukemia

Imatinib

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Clostridium botulinum

Antitoxin

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Clostridium dificile

Oral metronidazole

If refractory - oral vancomycin

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Clostridium tetani

Antitoxin

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CMV

Ganciclovir, Foscarnet, Ciodfovir

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Crohn’s disease

Corticosteroids, Infliximab, Azathioprine

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Cryptococcus neoformans

Fluconazole (in AIDS patients)

Diabetes Insipidus

Central: Desmopressin Nephrogenic: Hydrochlorothiazide, Indomethacin, Amiloride

Diabetes Mellitus Type 1

Dietary intervention (low carb) + Insulin replacement

Diabetes Mellitus Type 2

Dietary intervention, Oral hypoglycemics, and insulin (if refractory)

Diabetic Ketoacidosis

Fluids, Insulin, K+

Drug of choice for anticoagulation during preganancy

Heparin

Enterococci

Vancomycin, Aminopenicillins/Cephalosporins

Erectile dysfunction

Sildenafil, Tadalafil, Vardenafil

ER (+) breast cancer

Tamoxifen

Ethylene glycol/methanol intoxication

Fomepizole (Alcohol dehydrogenase inhibitor)

Haemophilus influenzae

Rifampin (prophylaxis)

Generalized anxiety disorder

SSRIs, SNRIs (first line) | Buspirone (second line)

Granulomatosis with polyangitis (GPA)

Cyclophosphamide, Corticosteroids

HER2/neu (+) breast cancer

Trastuzumab

Hyperaldosteronism

Spironolactone

Hypercholesterolemia

Statin (first line)

Hypertriglyceridemia

Fibrate

Immediate Anticoagulation

Heparin

Infertility

Leuprolide, GnRH (pulsatile) | Clomiphene

Influenza

Oseltamivir | Zanamivir

Kawasaki disease

IVIG, High dose aspirin

Legionella pneumo

Macrolides (eg. Azithromycin)

Long-term anticoagulation

Warfarin, Dabigatran, Ravaroxaban, and Apixaban

Malaria

Chloroquine, Mefloquine Atovaquone/Proguanil (for blood schizont) Primaquine (for liver hypnozoite)

Medical abortion

Mifepristone

Migraine

Acute attack: Sumatriptans, NSAIDs | Prophylaxis: Propranolol, Topiramate, CCBs, Amitriptyline

Multiple sclerosis

Disease modifying therapies (eg. B-Interferon, Natalizumab) | Acute flares: IV Steroids

Mycobacterium tuberculosis

``` RIPE: Rifampin Isoniazid Pyrazinamide Ethambutol ```

Neisseria gonorrhea

Ceftriazone (Add doxycycline to cover likely concurrent C trachomatis)

Neisseria meningitidis

Penicillin/Ceftriaxone, Rifampin (prophylaxis)

Neural tube Osteomalacia/Rickets

Vitamin D supplementation

Osteoporosis

Prophylaxis: Calcium/Vitamin D supplementation Treatment: Bisphosphonates, PTH analogs, SERMs, Calcitonin, Denosumab

Patent Ductus Arteriosus

``` PGE = OPEN Indomethacin = Close ```

Pneumocystis jirovecii

TMP-SMX | Pentamadine (second line or sulfa allergy)

Prolactinoma

Cabergoline/Bromocriptine | Dopamine agonists

Prostate adenocarcinoma

Flutamide

Pseudomonas aeruginosa

``` Ceftaz Pip/Tazo Aminoglycosides Carbapenems Ciprofloxacin ```

Pulmonary Arterial Hypertension (Idiopathic)

Sildenafil, Bosenta, Epoprostenol

Rickettsia rickettsii

Doxycycline | Chloramphenicol

Schizophrenia (negative symptoms)

Atypical antipsychotics (2nd Gen)

Schizophrenia (positive symptoms)

Typical antipsychotics (1st Gen)

SIADH

Fluid restriction, IV hypertonic saline, Conivaptan/Tolvaptan, Demeclocycline

Sickle Cell Disease

Hydroxyurea (increased fetal hemoglobin)

Sporothrix schenckii

Itraconazole, Oral potassium iodide

Stable angina

Sublingual nitroglycerin

Staph aureus

MSSA: Nafcillin, Oxacillin, Dicloxacillin MRSA: Vancomycin, Daptomycin, Linezolid, Ceftaroline

Step bovis

Penicillin prophylaxis | Evaluation for colon cancer if related to endocarditis

Strep pneumo

Systemic or Lung: Penicillin/Cephalosporin | Meningitis: Vancomycin

Step pyogenes

Penicillin prophylaxis

Temporal arteritis

High dose steroids

Tonic-Clonic seizures

Levetiracetam, Phenytoin, Valproate, Carbamazepine

Toxoplasmosis gondii

Sulfadiazene + Pyrimethamine

Treponema pallidum

Penicillin

Trichomonas vaginalis

Metronidazole (patient and partner)

Trigeminal neuralgia (Tic douloureux)

Carbamazepine

Ulcerative colitis

5-ASA preparations (Mesalamine) | 6-MP, Infliximab, Colectomy

UTI Prophylaxis

TMP-SMX

Warfarin reversal

``` Fresh frozen plasma (acute) Vitamin K (non-acute) ```