Autoantibodies Flashcards

1
Q

Anti-ACh

A

Myasthenia Gravis

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2
Q

Anti-Glomerular Basement Membrane

A

Goodpasture Syndrome

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3
Q

Anti-B2 Glycoprotein

A

Antiphospholipid Syndrome

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4
Q

Anticardiolipin, Lupus Anticoagulant

A

SLE, Antiphospholipid Syndrome

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5
Q

Anticentromere

A

Limited Scleroderma (CREST syndrome)

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6
Q

Anti-Desmoglein (Anti-Desmosome)

A

Pemphigus Vulgaris

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7
Q

Anti-Glutamic Acid Decarboxylase

Islet Cell Cytoplasmic Antibodies

A

Type I Diabetes Mellitus

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8
Q

Anti-Hemidesmosome

A

Bullous Pempigoid

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9
Q

Anti-Histidyl tRNA synthetase (Eg. Anti Jo-1)
Anti-SRP
Anti-Helicase (anti-M2)

A

Polymyositis

Dermatomyositis

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10
Q

Anti-Microsomal
Anti-Thyroglobulin
Anti-Thyroid Peroxidase

A

Hashimoto Thyroiditis

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11
Q

Anti-Mitochondrial

A

Primary Biliary Cirrhosis

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12
Q

Anti Parietal Cell

Anti-Intrinsic Factor

A

Pernicious Anemia

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13
Q

Antiphospholipase A2 Receptor

A

Primary Membranous Nephropathy

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14
Q

Anti-Scl 70

Anti-DNA Topoisomerase I

A

Scleroderma (Diffuse)

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15
Q

Anti-smooth muscle

A

Autoimmune Hepatitis Type I

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16
Q

Anti-SSA

Anti-SSB (Anti-Ro, Anti-La)

A

Sjogren Syndrome

17
Q

Anti-TSH Receptor

A

Grave’s Disease

18
Q

Anti-Presynaptic Voltage Gated Ca2+ Channel

A

Lambert-Eaton Myasthenic Syndrome

19
Q

IgA Anti-Endomysial

IgA Anti-Tissue Transglutaminase

A

Celiac Disease

20
Q

MPO-ANCA

p-ANCA

A

Microscopic Polyangitis
Eosinophilic Granumolatosis with Polyangitis (Churg Straus)
Ulcerative Colitis

21
Q

PR3-ANCA

c-ANCA

A

Granulomatosis with Polyangitis (Wegener)

22
Q

Rheumatoid Factor - IgM against IgG Fc region

Anti-CCP

A

Rheumatoid Arthritis

23
Q

Antinuclear (ANA)

A

Nonspecific screening antibody - often associated with SLE

24
Q

Anti-dsDNA

Anti-Smith

A

SLE

25
Q

Anti-Histone

A

Drug Induced SLE

26
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed Connective Tissue Disease

27
Q

Anti-Hu

A

Small Cell Lung Cancer

Paraneoplastic Cerebellar Degeneration

28
Q

Anti-Yo

A

Breast Cancer

Paraneoplastic Cerebellar Degeneration

29
Q

Anti-Tr

A

Hodgkin Lymphoma

Paraneoplastic Cerebellar Degeneration