Topic 2---B: Cell membranes- 1. Cell membranes- The basics Flashcards

1
Q

What are cell-surface membranes?

A
  • They surround cells
  • They are a barrier between the cell and it’s environment
  • They control which substances enter and leave the cell
  • They’re partially permeable so they let some molecules through but not others
  • Sometimes called the plasma membrane
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2
Q

How can substances move across the cell-surface membrane?

A

By
- Diffusion
- Osmosis
- Active transport

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3
Q

How do membranes around organelles divide the cell into different compartments?

A
  • They act as a barrier between the organelle and the cytoplasm
    E.g. The substances needed for respiration (like enzymes) are kept together inside a mitochondrion by the membrane surrounding the mitochondrion.
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4
Q

What components are in a membrane?

A
  • Phospholipids (7nm thick)
  • Proteins
  • Carbohydrates
  • Cholesterol
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5
Q

What was the ‘Fluid Mosaic Model’?

A
  • In 1972 Singer and Nicholson suggested it to describe the arrangement of molecules in the membrane.
  • In the model phospholipids molecules form a continuous, double layer (bilayer) which is ‘fluid’ because the phospholipids are constantly moving.
  • Proteins are scattered through the bilayer like tiles in a ‘mosaic’ (including channel and carrier proteins).
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6
Q

What do channel and carrier proteins do?

A

They allow large molecules and ions to pass through the membrane.

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7
Q

Phospholipids

A
  • Phospholipid molecules form a barrier to dissolved (water-soluble) substances.
  • They have a head (hydrophilic) which attracts water
  • They have a tail (hydrophobic) which repels water
  • Heads face out towards the water on either side of the membrane
  • Centre of the bilayer is hydrophobic so the membrane doesn’t allow water-soluble substances to diffuse through it
    e.g (ions& polar molecules)
  • Small, non-polar substances can diffuse through the membrane
    e.g (carbon dioxide and water)
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8
Q

Cholesterol

A
  • Present in all cell membranes apart from bacterial cell membranes
  • It gives the membrane stability
  • Cholesterol fits between the phospholipids
  • Cholesterol binds to the hydrophobic tails of the phospholipids causing them to pack more closely together
  • This restricts movement of the phospholipids making the membrane less fluid and more rigid
  • Cholesterol has hydrophobic regions so it’s able to create a further barrier to polar substances moving through the membrane
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9
Q

What does cholesterol help with?

A

It helps to maintain the shape of animal cells that don’t have cell walls
e.g (red blood cells)

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10
Q

Protein

A
  • Scattered through the bilayer
  • They allow molecules and ions to pass through the membrane
  • Receptor proteins on cell-surface membrane allow the cell- surface membrane to detect chemicals released from other cells
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11
Q

Carbohydrates

A
  • Glycoprotein (attatched to a protein)
  • Glycolipid (attatched to a lipid)
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12
Q

Functions (protein)

A
  • Act as a hydrophilic pore where water soluble substances can pass in or out of the cell
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13
Q

Phospholipid bilayer (function)

A
  • Allows water to pass through with relative ease
  • Acts as a barrier to the passage of water-soluble substances
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14
Q

Carbohydrate function

A
  • Helps stabilize the membrane structure by forming hydrogen bonds with water molecules outside the membrane
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15
Q

How does temperature affect membranes?

A
  • It affects how much the phospholipids in the bilayer can move
  • Affecting membrane structure and permeability
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16
Q

Temperatures below 0 degrees

A
  • Phospholipids don’t have much energy so they can’t move very much
  • They’re packed closely together and the membrane is more rigid
  • Channel and carrier proteins in the membrane denature (lose structure and function) so this increases the permeability of the membrane
  • Ice crystals may form and pierce the membrane making it highly permeable when it thaws
17
Q

Temperatures between 0 and 45 degrees

A
  • Phospholipids can move around and aren’t packed as tightly together
  • Membrane is partially permeable
  • As the temperature increases the phospholipids move more as they have more energy which increases the permeability of the membrane
18
Q

Temperatures above 45 degrees

A
  • Phospholipid bilayer starts to melt and the membrane becomes more permeable
  • Water inside the cell expands putting pressure on the membrane
  • Channel and carrier proteins in the membrane denature so they can’t control what enters or leaves the cell
  • This increases the permeability of the membrane