Tissues Flashcards
Type of connective tissue that supports and binds other tissues together
Cartilage
Type of CT that stores nutritional substances
Adipose tissue
which germ layer is the CT derived from?
Mesoderm
Where is the superficial fascia?
Between skin & underlying organs
Where is the deep fascia?
Bound to tendons & ligaments
Where is the subserous fascia?
Between the deep fascia and serous membranes
Fibres + ground substance =
Extracellular Matrix
What class of CT are the following; loose dense regular dense irregular elastic reticular adipose
types of CT proper
2 types of fluid CT
- Blood
2. Lymph
2 types of supporting CT
- Cartilage
2. Bone
What cells produce collagen, elastin and reticular fibres?
Fibroblasts
Difference between dense regular and dense irregular CT
regular = collagen fibres are parallel and unidirectional irregular = densely packed collagen fibres which are interwoven
What type of proper CT would you find in the liver & spleen?
Reticular
What support cell would you find in the cartilage?
Chondrocytes
Function of hyaline cartilage
Reduces friction between bony surfaces
Which cartilage is found in the trachea and bronchi?
Hyaline
Characterisitic of elastic cartilage
tolerates distortion without damage
Function of fibrocartilage
Prevents bone-to-bone contact
Which cartilage is found within the knee joints
Fibrocartilage
What compound makes the bone hard & rigid
Calcium phosphate
2 types of bone tissue
- Compact
2. spongy/cancellous
Cells contained within the vascular CT
Erythrocytes, leukocytes, thrombocytes, RBC, WBC
Surface & glandular are types of what
Epithelia
What are the 3 germ layers?
- Mesoderm
- Ectoderm
- Endoderm
Which is the 2 tissues originate from the ectoderm?
- Nervous
2. Epithelia
What holds membranes together in epithelia?
Intercellular junctions
Where is the apical (free) surface in epithelia?
Facing the lumen
Which epithelial cell lines blood vessels & air sacs?
Simple squamous
Which epithelial cell lines kidney tubules & glands?
Simple cuboidal
Location of simple columnar
lines digestive tract
Which epithelial cells secretes mucus through goblet cells (2)
- simple columnar
2. stratified columnar
What type of epithelial cell is on the outer layer of the skin?
Stratified squamous
What 2 components are found on the apical surface of epithelia?
- microvilli
2. Cilia
3 types of cell junctions
- Desmosomes
- Gap junctions
- Tight junctions
What protein is incorporated into desmosomes?
Cadherins
2 types of glands
- Exocrine
2. Endocrine
Branched duct system in glandular epithelium
Compound
Single tube system in glandular epithelium
Simple
Which colour marrow stores minerals, calcium salts & lipids
Yellow
Which colour marrow produced blood cells?
Red
2 layers of perichondrium
1) outer fibrous irregular CT layer
2) Inner cellular layer
Describe the arrangement of collagen fibres in hyaline cartilage
Closely packed
Describe the arrangement of collagen fibres in fibrocartilage
densely interwoven
Which type of cartilage absorbs shock?
Fibrocartilage
2 types of cartilager growth
- Interstitial growth
1. Appositional growth
What cell undergoes mitosis in interstitial growth?
Chondrocytes
What do fibroblasts differentiate into in appositional growth?
chondrocytes
What do chondrocytes secrete in appositional growth?
New matrix into perichondrium
2 forms of ossification
- Endochondral
2. Intramembranous
What cells produce spongy bone?
osteoblasts
What cells are osteoblasts derived from in endochondral ossificiation?
Fibroblasts
In intramembranous ossification what do mesenchymal cells differentiate into?
Osteoblasts
In intramembranous ossification, what replaces spongy bone?
Compact bone
What bones undergo intramembranous ossification?
- flat bones
- skull
- mandiable
- clavicle
What 3 arteries supply the bone?
- Nutrient artery
- Metaphyseal artery
- Periosteal artery
Which type of bone forms the diaphysis of bone?
Compact
What type of cell secretes enzymes that dissolve bone matrix?
Osteoclast
Which type of bone are osteons found in?
Compact bone
Which type of bone contains trabeculae?
Spongy bone
How do nutrients reach spongy bone, as it lacks capillaries?
By diffusion along the canaliculi
3 types of muscle
- Smooth
- Cardiac
- Skeletal
How to differentiate histological slides of cardiac and striated muscle?
The fibres in cardiac muscle are interconnected by intercalated discs
Name of CT sheath surrounding skeletal muscle?
Epimysium
CT layer surrounding a singlular fascicle?
Perimysium
What do muscle fibres consist of?
Muscle fibres
What cells are found within muscle fibres?
Satellite cells
Name of fibres in muscle fibres
Myofibrils
2 myofilaments in myofibrils
- actin
2. myosin
Resting MP=
-95mv
Function of T-tubules
allow rapid conduction of potential changes throughout muscle
Name of section of sarcoplasmic reticulum that enlarges and fuses to forms chambers (at the end)
Terminal cisternae
Which part of the muscle stores Ca2+
Sarcoplasmic reticulum
When the action potential is conducted along the T-tubule, where does Ca2+ travel to and from?
from sarcoplasmic reticulum to the sarcoplasm
Explain the movement of myofilaments during muscle contraction
Actin slide over myosin
Which part of myosin attaches to actin?
Myosin head
What other molecules are associated to actin? (2)
- Troponin
2. Tropomyosin
What is tropomysosin attached to?
Troponin
Name the binding sites of the 3 compartments of troponin:
- I
- T
- C
- Actin
- Tropomyosin
- Calcium
When troponin binds to calcium, its conformational shape is changed. what does this allow?
Tropomyosin to move away from the myosin binding site on actin
What triggers the opening of Na channel in the sarcolemma?
Binding of ACh to ACh receptors
What is ACh broken down by
AChE
Why is ACh broken down?
So that the muscle can stop contracting
After muscle contraction, how do Ca2+ return to the sarcoplamic reticulum?
Active transport pump, that uses ATP
What is tension in the muscle dependent on?
The number of cross bridges between actin and myosin
What is the relationship between degree of stretch and tension?
Positive
3 main phases of a twitch
- Latent period
- Contraction peroid
- Relaxation peroid
What is treppe, in terms of muscle contraction?
If the 2nd stimulation occurs immediately after the end of the relaxation phase, the next contraction will be slightly bigger.
What is incomplete tetanus?
Summation of contractions just after start of relaxation peroid. slowly induces tension.
What is incomplete tetanus?
Increasing stimulating frequency, eliminating the relaxation phase. contraction occurs upto maximum tension.
2 things that muscle tone enables
- maintenence of posture
2. maintenence of diameter of tubular structures to allow passage
2 types of contraction
- Isometric
2. Isotonic
2 types of isotonic contraction
- Eccentric
2. Concentric
In which type of isotonic contraction are cross bridges shortened?
Concentric
Name of CT surrounding 1 muscle fibre
Endomysium
Which filaments are in I bands?
Thin actin
Which filaments are in A bands?
Both thick and thin filaments
What type of cell junctions are in cardiac muscle?
- Gap
2. Desmosomes
What is the only thing that stimulates contraction in cardiac muscle?
Pacemaker cells
Explain distribution of myofilaments in smooth muscle
Scattered
Which type of muscle is multinucleated and fused?
skeletal