Tick Borne Flashcards

1
Q

Organism behind Lyme disease?

A

Borrelia burgdorferi

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2
Q

Vector for lyme disease>

A

Deer tick

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3
Q

Organism behind RMSF?

A

Rickettsia rickettsii

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4
Q

Vector for RMSF?

A

Dog Tick

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5
Q

Organism behind ehrlichiosis?

A

Ehrlichia chafeensis

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6
Q

Vector for Ehrlichiosis?

A

Lone star tick

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7
Q

Stage 1 of Lyme disease?

A

Localized rash 3-32 days

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8
Q

Stage 2 of Lyme disease?

A

Disseminated, cranial neuritis, skin lesions, meningitis

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9
Q

Stage 3 Lyme disease?

A

Knee joint arthritis, encephalopathy, polyneuropathy, acrodermatitis

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10
Q

Causes of CN 7 palsy?

A

Idiopathic (Bell’s Palsy), Herpes simplex virus (no rash), Herpes Zoster (vesicles in external auditory canal), and Lyme disease

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11
Q

What will you see in Chronic Lyme Disease?

A

Pain syndrome, chronic fatigue, and neurocognitive symptoms

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12
Q

Treatment of Lyme Disease?

A

Doxycycline

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13
Q

How to you test for LD?

A

IgM and IgG serologic testing

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14
Q

What vaccines are there for LD?

A

None for humans, canine vaccine is available

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15
Q

What in the body does RMSF ticks go for?

A

Vascular endothelial cells

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16
Q

Pathophysiology of RMSF?

A

Vasculitis, Hypoatremia, and thrombocytopenia

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17
Q

Classic triad of RMSF?

A

Fever, rash, and history of tick exposure

18
Q

How does the rash progress?

A

Starts as merciless, progresses to vasculitic rash involving palms and soles with petechiae

19
Q

What lab tests are done to diagnose RMSF?

A

Thrombocytopenia (low platelets)

Hypoatremia (low sodium)

20
Q

What tests can you do to test for RMSF?

A

Skin biopsy of lesion and serologic testing of IgM and IgG

21
Q

How do you treat RMSF?

A

Doxy except in pregnant women then use chloramphenicol

22
Q

What makes adult female of lone star tick easy to distinguish?

A

Big white spot

23
Q

Incubation period of Ehrlichiosis?

24
Q

Symptoms of Ehrlichiosis?

A

Fever, headache, myalgia

25
What lab findings will you see in Ehrlichiosis?
Leukopenia, thrombocytopenia, and elevated transaminases
26
How do you treat Ehrlichiosis?
Doxy
27
What causes Malaria?
Plasmodium species
28
What vector causes Malaria?
Anopheles mosquito
29
Which Plasmodium cause the most severe disease?
P. Falciparum
30
What do Plasmodium sporozoites target?
Hepatocytes
31
What causes hemolytic anemia in Malaria?
Lysing of RBC and release of merozoities to infect more
32
Which strains can produce dormant hypnozoities?
Vivax and ovale
33
What signs suggest Falciparum?
Seizures
34
What signs suggest vivid or ovale?
Paroxysmal chills, fever, rigors
35
What should turn your diagnosis away from Malaria?
Rash
36
What do thin and thick blood smears allow for?
Evaluation of ring forms and estimation of parasite load
37
What does thick blood smear do?
Concentrates parasites and increases diagnostic sensitivity
38
How do you treat non-falciparum malaria?
Chloroquine
39
How do you treat Falciparum?
Chloroquine if sensitive, Arteminsin preferred if Chloro is questioned
40
Why don't you use Mefloquine for prophylaxis
CNS side effects