Tick Borne Flashcards

1
Q

Organism behind Lyme disease?

A

Borrelia burgdorferi

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2
Q

Vector for lyme disease>

A

Deer tick

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3
Q

Organism behind RMSF?

A

Rickettsia rickettsii

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4
Q

Vector for RMSF?

A

Dog Tick

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5
Q

Organism behind ehrlichiosis?

A

Ehrlichia chafeensis

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6
Q

Vector for Ehrlichiosis?

A

Lone star tick

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7
Q

Stage 1 of Lyme disease?

A

Localized rash 3-32 days

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8
Q

Stage 2 of Lyme disease?

A

Disseminated, cranial neuritis, skin lesions, meningitis

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9
Q

Stage 3 Lyme disease?

A

Knee joint arthritis, encephalopathy, polyneuropathy, acrodermatitis

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10
Q

Causes of CN 7 palsy?

A

Idiopathic (Bell’s Palsy), Herpes simplex virus (no rash), Herpes Zoster (vesicles in external auditory canal), and Lyme disease

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11
Q

What will you see in Chronic Lyme Disease?

A

Pain syndrome, chronic fatigue, and neurocognitive symptoms

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12
Q

Treatment of Lyme Disease?

A

Doxycycline

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13
Q

How to you test for LD?

A

IgM and IgG serologic testing

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14
Q

What vaccines are there for LD?

A

None for humans, canine vaccine is available

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15
Q

What in the body does RMSF ticks go for?

A

Vascular endothelial cells

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16
Q

Pathophysiology of RMSF?

A

Vasculitis, Hypoatremia, and thrombocytopenia

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17
Q

Classic triad of RMSF?

A

Fever, rash, and history of tick exposure

18
Q

How does the rash progress?

A

Starts as merciless, progresses to vasculitic rash involving palms and soles with petechiae

19
Q

What lab tests are done to diagnose RMSF?

A

Thrombocytopenia (low platelets)

Hypoatremia (low sodium)

20
Q

What tests can you do to test for RMSF?

A

Skin biopsy of lesion and serologic testing of IgM and IgG

21
Q

How do you treat RMSF?

A

Doxy except in pregnant women then use chloramphenicol

22
Q

What makes adult female of lone star tick easy to distinguish?

A

Big white spot

23
Q

Incubation period of Ehrlichiosis?

A

8 days

24
Q

Symptoms of Ehrlichiosis?

A

Fever, headache, myalgia

25
Q

What lab findings will you see in Ehrlichiosis?

A

Leukopenia, thrombocytopenia, and elevated transaminases

26
Q

How do you treat Ehrlichiosis?

A

Doxy

27
Q

What causes Malaria?

A

Plasmodium species

28
Q

What vector causes Malaria?

A

Anopheles mosquito

29
Q

Which Plasmodium cause the most severe disease?

A

P. Falciparum

30
Q

What do Plasmodium sporozoites target?

A

Hepatocytes

31
Q

What causes hemolytic anemia in Malaria?

A

Lysing of RBC and release of merozoities to infect more

32
Q

Which strains can produce dormant hypnozoities?

A

Vivax and ovale

33
Q

What signs suggest Falciparum?

A

Seizures

34
Q

What signs suggest vivid or ovale?

A

Paroxysmal chills, fever, rigors

35
Q

What should turn your diagnosis away from Malaria?

A

Rash

36
Q

What do thin and thick blood smears allow for?

A

Evaluation of ring forms and estimation of parasite load

37
Q

What does thick blood smear do?

A

Concentrates parasites and increases diagnostic sensitivity

38
Q

How do you treat non-falciparum malaria?

A

Chloroquine

39
Q

How do you treat Falciparum?

A

Chloroquine if sensitive, Arteminsin preferred if Chloro is questioned

40
Q

Why don’t you use Mefloquine for prophylaxis

A

CNS side effects