HIV Flashcards

1
Q

What were the “4 H’s”?

A

Heroin, Homosexual, Haitains, and Hemophilliac

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2
Q

How is HIV screen for now?

A

HIV RNA (plasma)

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3
Q

How long until 3rd generation antibody tests can detect HIV?

A

10 days

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4
Q

Most commonly reported symptom of HIV?

A

Fever and fatigue

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5
Q

Can a low CD4 cell count be diagnostic of HIV?

A

No, have to use HIV antibody testing

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6
Q

What happens if the ELISA test is positive?

A

You do it again.

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7
Q

What happens if 2nd ELISA test is positive?

A

You run a Western Blot test

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8
Q

What is the main marker for HIV disease progression?

A

CD4

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9
Q

Normal range of CD4?

A

350 to 1100/mm3

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10
Q

How can we measure viral RNA in plasma?

A

PCR or branched DNA techniques

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11
Q

How will HIV present at CD4 count >500/mm3?

A

Asymptomatic

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12
Q

How will HIV present at CD4 count 500-200?

A

Asymptomatic, generalized adenopathy, thrush, and Kapok’s sarcoma

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13
Q

CD4

A

PCP, toxoplasmosis, and cryptococcus

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14
Q

CD4

A

CMV and mycobacterium increased risk

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15
Q

When do you start HIV treatment?

A

CD4 cell count

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16
Q

What is Lipodystrophy syndrome?

A

Body morphology changes and metabolic complications

17
Q

Where is AIDs the worst?

A

Sub-Sahara Africa

18
Q

How did HIV spread?

A

Africa to Haiti and then Haiti to U.S

19
Q

Easiest way to get HIV?

A

Blood transfusion (90%)

20
Q

Hardest way to get HIV?

A

Insertive oral intercourse (0.005%)

21
Q

How often should you screen people at high risk for HIV?

A

Once a year

22
Q

What are two HIV opportunistic associated diseases?

A

Pneumocystis pneumonia

Kaposi’s sarcoma

23
Q

An abrupt onset of 10 signs and symptoms in 24 hours would be indicative of what?

A

Primary HIV infection

24
Q

What is the highly sensitive screen test used for HIV antibody testing?

A

ELISA (Enzyme linked immunosorbent assay)

25
What happens if the ELISA comes up as negative?
HIV antibodies reported as negative
26
What happens if the ELISA comes up as positive?
You repeat it a second time
27
What happens if the second ELISA test is positive?
You do a western blot test
28
What constitutes a positive WB test?
2 of the 3 specific bands show up
29
How do you measure viral RNA in plasma?
PCR or branched DNA techniques
30
What type of vaccines do you want to avoid giving an HIV patient?
Live
31
Which pathogen has the highest risk of seroconversion after percutaneous exposure?
Hep B (30%)
32
Was Zidovudine protective against HIV?
yes
33
Was is the correlation between HIV viral load and % to transmit to newborn?
The higher the HIV viral load the higher the likelihood to transmission
34
LDH value in Pneumocystis Pneumonia patients?
Elevated
35
How do you treat Pneumocystis Pneumonia?
Corticosteroids or antimicrobials
36
CD4 count less than 50 leads to what?
CMV and mycobacterium avid complex Increased risk of lymphoma Highest mortality