Intro to Rheumatology Flashcards
Where are collagen fibers anchored?
Subchondral bone
What do chondrocytes produce?
Cartilage
What gives cartilage its elasticity?
Pressure of bound water
Cartilage vascular system?
Avascular
What gives the chondrocytes nutrition?
Synovial fluid produced by synovial membrane
How thick is the synovial membrane?
1-3 cells thick
1 rheumatoid disease?
Osteoarthritis
Rapidity of onset for rheumatoid problems?
Gout timed to a minute
RA days to weeks
Fibromyalgia slow and indolent
What does Gout respond really well to?
NSAIDS
What does Fibromyalgia respond well to?
Exercise
CBCs and chemistries are done why?
Assess for systemic involvement of disease process
Determine contraindications to therapies
What are two acute phase reactants commonly missed?
Hemoglobin, albumin
Examples of DMARDs?
Hydroxychloroquin
Gold
Methotrexate