Osteoporosis

Question 1

What characterizes Osteoporosis? (4)

Answer 1

Low bone mass
Deterioration of bone tissue
Compromised bone strength
Increased risk of fracture

Question 2

What factors determine peak bone mass? (4)

Answer 2

Genetics
Nutrition
Endocrine status
Physical activity and health during growth

Question 3

Increased bone loss by? (4)

Answer 3

Aging
Hypogonadism
Menopause
High bone turnover

Question 4

Osteoclastic activity?

Answer 4

Removing older bone

Question 5

Osteoblastic activity?

Answer 5

Replacing old bone with new bone

Question 6

Where are the changes in osteoporosis?

Answer 6

Cancellous bone

Thinning of trabeculae

Question 7

Women of what age are more at risk?

Answer 7

Over 50, postmenopausal

Question 8

What dietary inadequacies can cause osteoporosis? (4)

Answer 8

Low calcium
Low Vit D
Excess Vit A
Excess salt

Question 9

Cystic fibrosis causes a problem with what in bones?

Answer 9

Absorption

Question 10

Turners is what chromosome defect?

Answer 10

XO

Question 11

Klinefelter’s are what chromosome problem?

Answer 11

XXY

Question 12

Cushing’s syndrome or exogenous corticosteroids cause whaT?

Answer 12

Corticosteroid excess

Question 13

Hyperparathyroid results in what?

Answer 13

Too much calcium taken from the bone

Question 14

Gastrointestinal disorders affect what in osteoporosis?

Answer 14

Absorption

Question 15

Fractures of dorsal spine can lead to what?

Answer 15

Increasing kyphosis

Question 16

Main screen and diagnostic study for osteoporosis?

Answer 16

DEXA (Dual xray absorbiometry

Question 17

DEXA is based on what?

Answer 17

Density, not morphology

Question 18

What is osteomalacia?

Answer 18

Impaired mineralization of the bony matrix

Question 19

Neoplasm metastatic to bone can cause what?

Answer 19

Compression fractures

Question 20

Therapy? (2)

Answer 20

Weight bearing

Muscle strengthening exercise