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TOP 300 > Thyroid Medications > Flashcards

Thyroid Medications Flashcards

1
Q

generic name

synthetic thyroxine (T4)

A

levothyroxine

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2
Q

brand name

synthetic thyroxine (T4)

A

synthroid

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3
Q

indication

synthetic thyroxine (T4)

A

hypothyroidism

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4
Q

MOA

synthetic thyroxine (T4)

A

T4 is a synthetic form of thyroxine, an endogenous hormone secreted by the thyroid gland

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5
Q

contraindications

synthetic thyroxine (T4)

A
  • Uncorrected adrenal insufficiency
  • Thyrotoxicosis
  • Benign thyroid nodules
  • acute MI (myocardial infarction)
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6
Q

black box warnings

synthetic thyroxine (T4)

A

should not be used for weight reduction

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7
Q

common ADRs

synthetic thyroxine (T4)

A
  • anxiety
  • decreased appetite
  • diarrhea
  • insomnia
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8
Q

rare but serious ADRs

synthetic thyroxine (T4)

A
  • Aggravation of pre-existing CV disease
  • hyperthyroidism
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9
Q

key counseling points

synthetic thyroxine (T4)

A
  • Take consistently on an empty stomach each day (with water and at least 30 min before food)
  • Separate calcium and iron-containing products by at least 4 hours
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10
Q

brand name

dessicated thyroid

A

armour thyroid

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11
Q

generic name

dessicated thyroid

A

thyroid

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12
Q

indication

dessicated thyroid

A

hypothyroidism

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13
Q

MOA

dessicated thyroid

A

derived thyroid replacement containing both levothyroxine (T4) and liothyronine (T3)

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14
Q

contraindications

dessicatd thyroid

A
  • Untreated thyrotoxicosis
  • Uncorrected adrenal insufficiency
  • Myxedema
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15
Q

black box warnings

dessicated thyroid

A

should not be used for weight reduction

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16
Q

common ADRs

dessicated thyroid

A
  • hair loss
  • diarrhea
  • nausea/vomiting
  • weight loss
17
Q

rare but serious ADRs

dessicated thyroid

A
  • Aggravation of pre-existing CV disease
  • hyperthyroidism
18
Q

key counseling points

dessicated thyroid

A
  • Take consistently each day on an empty stomach (30 to 60 minutes prior to breakfast) to increase absorption
  • Some desiccated thyroid products are acquired from porcine thyroid gland (pork)
19
Q

generic name

antithyroid agents

A

potassium iodide

20
Q

brand name

antithyroid agents

A

SSKI & ThyroShield

21
Q

indication

antithyroid agents

A

hyperthyroidism

22
Q

MOA

antithyroid agents

A

inhibits release of thyroid hormones via direct effect of thyroid gland

23
Q

contraindications

antithyroid agents

A

nodular thyroid condition with heart disease

24
Q

common ADRs

antithyroid agents

A
  • GI upset
  • diarrhea
  • nausea/vomiting
  • salivary gland swelling
25
Q

rare but serious ADRs

antithyroid agents

A
  • Hypersensitivity Reaction
  • Hypothyroidism
  • Thyroid
    adenoma/Goiter
26
Q

key counseling points

antithyroid agents

A
  • Take with food to minimize GI upset
  • Take with 4 oz of water. Other liquids can be used; dilution in chocolate milk can help mask the taste

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