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TOP 300 > Antidepressants > Flashcards

Antidepressants Flashcards

1
Q

generic name and class

brand: Elavil

A

generic: amitriptyline
class: tricyclic antidepressant (TCA)

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2
Q

brand name and class

generic: Doxepin

A

brand: sinequan, silenor
class: tricyclic antidepressant (TCA)

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3
Q

generic name and class

brand: Pamelor

A

generic: Nortriptyline
class: tricyclic antidepressant (TCA)

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4
Q

brand name and class

generic: Citalopram

A

brand: Celexa
class: selective serotonin reuptake inhibitor (SSRI)

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5
Q

generic name and class

brand: lexapro

A

generic: escitalopram
class: selective serotonin reuptake inhibitor (SSRI)

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6
Q

brand name and class

generic: fluoxetine

A

brand: prozac, sarafem
class: selective serotonin reuptake inhibitor (SSRI)

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7
Q

brand name and class

generic: paroxetine

A

brand: paxil, paxil cr
class: selective serotonin reuptake inhibitor (SSRI)

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8
Q

generic name and class

brand: zoloft

A

generic: sertraline
class: selective serotonin reuptake inhibitor (SSRI)

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9
Q

brand name and class

generic: desvenlafaxine

A

brand: pristiq, khedezla
class: serotonin norepinephrine reuptake inhibitor (SNRI)

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10
Q

brand name and class

generic: duloxetine

A

brand: cymbalta
class: serotonin norepinephrine reuptake inhibitor (SNRI)

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11
Q

generic name and class

brand: effexor, effexor xr

A

generic: venlafaxine
class: serotonin norepinephrine reuptake inhibitor (SNRI)

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12
Q

generic name and class

brand: aplenzin, forfivo, wellbutrin, zyban

A

generic: bupropion
class: miscellaneous AD

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13
Q

generic name and class

brand: remeron

A

generic: mirtazapine
class: miscellaneous AD

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14
Q

brand name and class

generic: vilazodone

A

brand: viibryd
class: miscellaneous AD

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15
Q

MOA for TCAs

amitriptyline, doxepin, nortriptyline

A

inhibit reuptake of norepinephrine and serotonin

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16
Q

MOA for SSRIs

citalopram, escitalpram, fluoxetine, paroxetine, and sertraline

A

inhibits reuptake of serotonin

17
Q

MOA for SNRIs

desvenlafaxine, duloxetine, and venlafaxine

A

serotonin norepinephrine reuptake inhibitors

18
Q

MOA for AD-misc

bupropion, mirtazapine, and vilazodone

A

Bupropion: NE-DA
Mirtazapine: 5HT/NE-hist
Vilazodone: 5HT

19
Q

contraindications for SSRIs

citalopram, escitalpram, fluoxetine, paroxetine, and sertraline

A

concomitant use of MAOIs

20
Q

BBW for SSRIs

citalopram, escitalpram, fluoxetine, paroxetine, and sertraline

A

suicidality

21
Q

ADRs for TCAs

amitriptyline, doxepin, nortriptyline

A
  • sedation
  • seizure
  • anticholinergic effects
  • CV heart block
  • orthostatic hypotension
  • tachycardia
22
Q

ADRs for SSRIs

citalopram, escitalpram, fluoxetine, paroxetine, and sertraline

A
  • abnormal bleeding, hyponatremia
  • serotonin syndrome
  • seizures
  • activation of mania
  • angle closure glaucoma
  • discontinuation syndrome
  • sexual dysfunction
23
Q

ADRs for SNRIs

desvenlafaxine, venlafaxine, and dulxetine

A
  • abnormal bleeding
  • hyponatremia
  • serotonin syndrome
  • seizures
  • activation of mania
  • angle closure glaucome
  • discontinuation syndrome
  • suicide boxed warning
  • sexual dysfunction
  • elevated blood pressure
24
Q

ADRs for AD-misc

bupropion, mirtazapine, and vilazodone

A
  • suicide boxed warning
  • activation of mania
  • CYP drug interactions
25
Q

key counseling points

all ADs

A
  • takes up to 4-6 weeks to take effect
  • side effects like stomach upset, nausea and diarrhea should decrease with continued use. feeling anxiety with first few doses is common
  • sexual side effecrs are common and don’t resolve with continued use
  • contact MD if changes in mood, thinking or behavior
  • do not drive or operate machinery after first dose until you know how meds will affect you
  • if med makes you drowsy take at bedtime. if med makes you restless take in morning w/o regard to food at either time of day
  • do not take other meds without checking with MD or RPh
  • avoid alcohol and recreational substances

TOP 300 (19 decks)

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