Pulmonary and Anaphylaxis Flashcards
indication for pulmonary medications
asthma, chronic obstructive pulmonary disease (COPD)
why inhale medications?
direct delivery of medication to site of action in the lungs and fewer systemic side effects
anaphylaxis agent
name
epinephrine
indication of epipen
emergency treatment of acute anaphylaxis due to allergic reactions
common adverse drug reactions for epipen
anxiety, apprehension, headache, nausea, palpitations, pale complexion, restlessness, sweating and tremors
rare but serious adverse drug reactions for epipen
angina, cardiac dysthrhythmia, pulmonary edema, ventricular fibrillation
key counseling points for anaphylaxis agent
- proper administration of autoinjector (IM injection)
- immediately seek emergency care after administration even if feeling better
mechanism of action for anaphylaxis agent
epinephrine binds to adrenergic receptors
if epinephrine binds to alpha adrenergic receptors
vasoconstriction which leads to increased blood pressure
if epinephrine binds to beta-1 adrenergic receptors
increased heart rate and increased contractility which leads to increased cardiac output
if epinephrine binds to beta-2 adrenergic receptors
bronchodilation which leads to improved breathing
major contraindications in anaphylaxis agent
none in emergency situations
brand name of anaphylaxis agent
EpiPen Autoinjectior
generic name of anaphylaxis agent
epinephrine
generic name of leukotriene receptor antagonist
montelukast
brand name of leukotriene receptor antagonist
singulair
indication of montelukast
asthma (maintenance)
exercise induced bronchospasm
allergic rhinitis
mechanism of action for leukotriene receptor antagonist
binds leukotriene receptors to inhibit their effect which results in bronchodilation
major contraindications of leuktriene receptor antagonist
hypersensitivity
black box warnings of leukotriene receptor antagonist
behavior and mood effects (including suicide and suicidal thoughts)
common adverse drug reactions for montelukast
dizziness, headache, fatigue (well tolerated)
rare adverse drug reactions for montleukast
aggressive or altered behavior, suicidal thoughts, cholestatic hepatitis, allergic granulomatous angitis
counseling points for leukotriene receptor antagonist
not for quick relief
given at bedtime
short acting beta 2 agonists (SABAs) generic name
albuterol
short acting beta 2 agonists (SABAs) brand name
proventil HFA
ventolin HFA
proair
indication for SABAs
acute symptom relief in asthma and COPD, prevention of exercise induced asthma (rescue med)
MOA for SABAs
stimulates beta 2 receptors in the airways, causes bronchial smooth muscle relaxation