Thyroid (Exam #3) Flashcards
Is hypothyroidism associated with high I- or low I-?
LOW I-
Is hyperthyroidism associated with high I- or low I-?
HIGH I-
Sxs of weight gain, cold sensitivity, fatigue are indicative of what?
Hypothyroidism
- Myxedema coma if severe
The function of what enzyme MUST be good in order to administer Levothyroxine (Synthroid)?
Peripheral deiodinases
- Converts T4 to T3
Which Hypothyroid medication is used as initial therapy? Which is used as maintenance? Why is this?
Liothyronine sodium = T3 = initial
- Faster steady state so acts fast
Levothyroxine (Synthroid) = T4 = maintenance
- Takes 5 weeks to reach study state so takes time to work
Of the three Hypothyroid medications, which involves T4? T3? T4 AND T3?
- Levothyroxine (Synthroid) = T4
- Liothyronine sodium = T3
- Desiccated Thyroid = T4 AND T3
Sxs of tachycardia, heat sensitivity, tremor, insomnia, diarrhea, fatigue are indicative of what?
Hyperthyroidism
Four treatment options for Hyperthyroidism?
- BB for sxs relief
- Thioamides or Iodide (reduce T4, T3)
- 131I
- Surgery
Which Hyperthyroid medication is used short-term? Which is used as maintenance? Why is this?
- Iodide = short-term
- Thioamides = maintenance (gradual effects)
Use of Iodide (2)?
- 7-10 before surgery (SHORT TERM ONLY)
- Radioacative emergency
For what two reasons would PTU be used over Methimazole?
- Pregnancy
- Allergy to Methimazole
Two uses of Radioactive Iodine (131I)?
- Diagnostic = small amounts
- Destroy thyroid gland = large amounts