Thyroid (Exam #3) Flashcards

1
Q

Is hypothyroidism associated with high I- or low I-?

A

LOW I-

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2
Q

Is hyperthyroidism associated with high I- or low I-?

A

HIGH I-

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3
Q

Sxs of weight gain, cold sensitivity, fatigue are indicative of what?

A

Hypothyroidism

- Myxedema coma if severe

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4
Q

The function of what enzyme MUST be good in order to administer Levothyroxine (Synthroid)?

A

Peripheral deiodinases

- Converts T4 to T3

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5
Q

Which Hypothyroid medication is used as initial therapy? Which is used as maintenance? Why is this?

A

Liothyronine sodium = T3 = initial
- Faster steady state so acts fast

Levothyroxine (Synthroid) = T4 = maintenance
- Takes 5 weeks to reach study state so takes time to work

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6
Q

Of the three Hypothyroid medications, which involves T4? T3? T4 AND T3?

A
  • Levothyroxine (Synthroid) = T4
  • Liothyronine sodium = T3
  • Desiccated Thyroid = T4 AND T3
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7
Q

Sxs of tachycardia, heat sensitivity, tremor, insomnia, diarrhea, fatigue are indicative of what?

A

Hyperthyroidism

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8
Q

Four treatment options for Hyperthyroidism?

A
  • BB for sxs relief
  • Thioamides or Iodide (reduce T4, T3)
  • 131I
  • Surgery
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9
Q

Which Hyperthyroid medication is used short-term? Which is used as maintenance? Why is this?

A
  • Iodide = short-term

- Thioamides = maintenance (gradual effects)

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10
Q

Use of Iodide (2)?

A
  • 7-10 before surgery (SHORT TERM ONLY)

- Radioacative emergency

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11
Q

For what two reasons would PTU be used over Methimazole?

A
  • Pregnancy

- Allergy to Methimazole

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12
Q

Two uses of Radioactive Iodine (131I)?

A
  • Diagnostic = small amounts

- Destroy thyroid gland = large amounts

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