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Pharmacology II > EXAM #2 DOCs > Flashcards

EXAM #2 DOCs Flashcards

1
Q

NON-Sulfa Diuretic?

A

Ethacrynic Acid (Loop)

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2
Q

Diuretics that work at low GFR (2)?

A
  • Loops

- Metolazone (Thiazide)

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3
Q

Eplerenone vs Spironolactone (2)?

A
  • SARA (fewer endocrine AEs)

- Drug interactions (metabolized by CYP3A4)

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4
Q

NON-acid Diuretics (2)?

A
  • Amiloride (K-sparing)

- Triamterene (K-sparing)

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5
Q

DOC for Lithium-induced DI?

A

Amiloride (K-Sparing Independent of Aldosterone)

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6
Q

DOC for Hyperaldosteronism?

A

Spironolactone (K-Sparing Aldosterone Antagonist)

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7
Q

Treats Central DI?

A

Desmopressin (ADH Agonist)

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8
Q

Treats euvolemic or hypervolemic hyponatremia (SIADH)?

A

Conivaptan (ADH Antagonist)

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9
Q

DECREASE preload (2)?

A
  • Diuretics

- Venodilators

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10
Q

DECREASE afterload?

A

Arteriodilators

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11
Q

INCREASE contractility (3)?

A

Inotropic drugs

  • Dobutamine
  • Dopamine
  • Digoxin
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12
Q

REDUCE energy expenditure of heart (decrease HR)?

A

B-Blockers

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13
Q

DOC for HF?

A

ACE-I = “-prils”

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14
Q

Soon-to-be DOC for HF? Why?

A

ARNI (Ernesto)

- Better at reducing mortality compared to ACE-I alone

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15
Q

DOC for HTN in pregnancy (3)?

A
  • Methyldopa
  • Nifedipine
  • Labetalol
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16
Q

DOC for HTN + Angina (2)?

A
  • BB

- CCB

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17
Q

DOC for HTN + POST-MI (2)?

A
  • ACE-I/ARB

- BB

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18
Q

DOC for HTN + HF (4)?

A
  • ACE-I/ARB
  • BB
  • Aldosterone Antagonist
  • Diuretics
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19
Q

DOC for HTN + CKD?

A

ACE-I/ARB

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20
Q

DOC for diabetic nephropathy?

A

ACE-I/ARB

- CKD in general

21
Q

DOC for HTN + DM (2)?

A
  • ACE-I/ARB

- CCB

22
Q

DOC for HTN + Asthma (2)?

A
  • ACE-I

- CCB

23
Q

DOC for HTN + BPH?

24
Q

3 HIP drugs and what they lead to?

A

Lead to Lupus (SLE)

  • Hydralazine
  • INH
  • Procainamide
25
DOC for EMERGENT HTN in pregnancy?
Hydralazine
26
DOC for Variant Angina (2)?
- Nitrites/Nitrates | - CCBs (specifically, "-dipines")
27
DOC for ACUTE Angina (classic or variant)?
Nitrites/Nitrates
28
DOC for Hyperlipidemia?
Statins
29
DOC for Hyperlipidemia in pregnancy?
Resins | - Cholestyramine
30
Most effective agent for increasing HDL?
Niacin
31
"Broad spectrum" antiarrhythmic?
Quinidine (Class IA)
32
DOC for acute ventricular arrhythmias?
Lidocaine = IV (Class IB)
33
DOC for ventricular arrhythmias?
Amiodarone = oral or IV (Class III)
34
DOC for ACUTE PSVT (3)?
- Adenosine = IV (other) - Esmolol = IV (Class II) - CCBs = oral or IV (Class IV)
35
DOC for CHRONIC PSVT (2)?
- BB (Class II) | - CCBs (Class IV)
36
DOC for Torsades de Pointe tx?
Magnesium (other)
37
All antiarrhythmics can treat supraventricular AND ventricular arrhythmias EXCEPT which which two classes?
Class IB = ventricular ONLY - Lidocaine Class IV = supraventricular ONLY - Verapamil - Diltiazem
38
Which four antiarrhythmics are IV ONLY?
- Lidocaine (Class IB) - Esmolol (Class II) - Adenosine (Class III) - Magnesium (other)
39
STRONGEST antiarrhythmic?
Flecainide (Class IC)
40
DOC for ACUTE PSVT and WPW Syndrome?
Adenosine (Class III)
41
DOC to prevent thrombosis in patients WITH coronary stents? What is it soon to be replaced with?
Current: Clopidogrel (Plavix) | - Ticagrelor (Brilinta) = soon-to-be
42
DOC for anticoagulation in pregnancy (2)
LMWH - Enoxaprin - Fondaparinux
43
Antidote for Heparin? What form is it NOT effective in?
Protamine sulfate | - NOT effective for Fondaparinux
44
Antidote for Direct Thrombin Inhibitors = Dabigatran (Pradaxa)?
Idarucizumab (Praxbind)
45
Antidote for Direct Factor Xa Inhibitors = Rivaroxaban (Xarelto) or Apixaban (Eliquis)?
Factor Xa (Andexxa)
46
Antidote for Warfarin (2)? Which is immediate?
- Vitamin K = takes time | - FFP = IMMEDIATE
47
Antidote for Fibrinolytics = Alteplase/t-PA (2)?
Antifibrinolytics - Aminocaproid acid - Tranexamic acid
48
Treat pulmonary edema? HOW?
Loops | - Increase systemic capacitance to reduce pulmonary congestion
49
DOC for Hyperlipidemia + high-risk ASCVD patients? What dose?
Atorvastatin | - HIGH-INTENSITY dosage

Pharmacology II (20 decks)

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