EXAM #3 CIs

Question 1

CIs of Estrogen (5)?

Answer 1

• Estrogen-dependent CA
• Clotting disorders
• Uncontrolled HTN
• Smoker/35+ years
• Pregnancy

Question 2

CIs of combination contraception (P + E) (7)?

Answer 2

• ASCVD
• Thromboembolic condition
• E-dependent CA
• Pregnancy
• Smoker AND 35+ years
• HTN
• DM

Question 3

Relative CI of combination contraception (P + E)?

Answer 3

Liver disease

Question 4

CI of Finasteride (Propecia)?

Answer 4

Pregnancy = teratogenic

Question 5

CI of Metformin? What other two should be considered?

Answer 5

KIDNEY DISEASE (processed by kidneys and increased risk for lactic acidosis)

• Hepatic disease
• Alcoholism

Question 6

Three DM drugs/classes that are CI for renal disease?

Answer 6

• Metformin
• SGLT2 Inhibitors
• Sitagliptin (DPP-4 Inhibitor)

Question 7

DM class that is CI for HF?

Answer 7

TZDs

Question 8

CIs of GLP-1 Receptor Agonists (2)?

Answer 8

• Acute/hx of pancreatitis

- Thyroid CA

Question 9

CI of DPP-4 Inhibitors (2 - which is an exception)?

Answer 9

• Acute/hx of pancreatitis

- Renal impairment (except Linagliptin bc not renally excreted)

Question 10

CI of SGLT2 Inhibitors?

Answer 10

KIDNEY DISEASE/DIALYSIS

Question 11

CIs of TZDs (2)?

Answer 11

• HF

- Liver disease

Question 12

CI of Acarbose and Miglitol?

Answer 12

GI disease

Question 13

CI of SUs?

Answer 13

Allergy to Sulfa drugs

Question 14

CI of Oxytocin?

Answer 14

Any time vaginal delivery NOT recommended

Question 15

CI of Ergonovine maleate (2)?

Answer 15

• NEVER use to induce labor (contractions are strong and continuous)
• PVD/CAD (acts on alpha receptors)

Ergot Alkaloids

Question 16

CI for Radioactive Iodine (131I)?

Answer 16

Pregnancy

Question 17

CI for Propranolol (2)? Alternative treatment?

Answer 17

• Asthma (use CCBs instead)

- DM

Question 18

CI of Teriparatide and Abaloparatide?

Answer 18

Osteosarcoma = BLACK BOX warning

Question 19

CIs of Denosumab (2)?

Answer 19

• Hypocalcemia (TREAT FIRST)

- Pregnancy

Question 20

CI of Alendronate, Risedronate, Ibandronate, Zoledronic Acid (3 - consider admin)?

Answer 20

• Inability to stand/sit up (oral)
• Esophageal disease (oral)
• Renal disease (IV)

Question 21

CI of Adrenal Insufficiency?

Answer 21

NONE

- If replacement is needed, give drugs

Question 22

With Adrenal Insufficiency, what conditions should be considered relatively (7)?

Answer 22

• Infection
• DM
• CVD/HTN
• Osteoporosis
• IC
• Childhood
• Pregnancy

Question 23

CI of Ketoconazole?

Answer 23

• Pregnancy = teratogenic