Thyroid disorder Flashcards
1
Q
autoimmune in which body attack thyroid hormone.
A
HashimOtO (hypO)
2
Q
MOA of PTU
A
Inhibit TPO.
At high doses inhibits conversion of peripheral conversion of T4 to T3 by inhibiting 5-monodeiodinase.
3
Q
Drug of choice in pregnancy for hyperthyroidism. why
A
PTU.
Preferred in pregnancy because it has more protein binding and less absorption into placenta.
4
Q
t1/2 of PTU
A
only 2 hours
5
Q
Peak serum levels of PTU
A
seen after 1-hour
6
Q
Comparing PTU and methimazole, which is Secreted LESS in breast milk
A
PTU
7
Q
Methimazole and PTU which is a hypERthyroidism drugs comes under which structural class
A
THIONAMIDES
