Thyroid Conditions in Pregnancy

Question 1

what can cause anovulatory cycles?

Answer 1

hypo and hyperthyroidism

Question 2

what is maternal thyroxine important for in neonatal development?

Answer 2

CNS development

Question 3

what can increased demand in pregnancy for thyroxine lead to?

Answer 3

goitre

Question 4

what does hCG do?

Answer 4

increases thyroxine which suppresses TSH

hCG effect increases T4 (hyperemesis gravidarum)

Question 5

how to distinguish hyperthyroidism and hyperemesis gravidarum?

Answer 5

check TRAb and it should resolve by 20 weeks gestation

Question 6

management of hyperemesis gravidarum

Answer 6

wait and see

beta blockers if needed

Question 7

hyperthyroidism management during pregnancy

Answer 7

PTU for 1st trimester

carbimazole for 2nd and 3rd trimester

Question 8

what increases the risk of post-partum thyroiditis?

Answer 8

T1DM

Question 9

what is post-partum thyroiditis?

Answer 9

transient hypothyroidism for up to a year that is associated with postnatal depression