4th Year Thyroid Flashcards

1
Q

examples of iatrogenic causes of hyperthyroidism

A

amiodarone (full of iodine)
levothyroxine
contrast medium

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2
Q

how long does it take carbimazole to work?

A

6 weeks so use propranolol for symptom management

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3
Q

exogenous causes of thyrotoxicosis

A

iodine excess
contrast media
drugs
postpartum

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4
Q

risk in using RAI in active hyperthyroidism?

A

risks thyroid storm

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5
Q

complications in thyroidectomy

A

parathyroids

laryngeal nerve palsy (hoarse voice)

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6
Q

main RF for Grave’s eye disease

A

smoking

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7
Q

management of Grave’s eye disease

A
artificial tears
sunglasses
avoid dust
elevate bed when sleeping to reduce periorbital oedema 
steroids
surgical decompression
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8
Q

do neoplasms/ cancers tend to be euthyroid?

A

yes

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9
Q

what does RAI require the patient to do?

A

isolate
use own cutlery
use contraception as do not want to get pregnant

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10
Q

management of thyroid storm

A

beta blockers
PTU
hydrocortisone if likely Addison’s aswell

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11
Q

why is PTU first line in thyroid storm?

A

more rapid onset than carbimazole

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12
Q

what condition to consider in myxoedema coma?

A

Addison’s

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13
Q

how often are TFTs done when on levothyroxine?

A

every 6 months

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14
Q

what kind of receptor does T3 and T4 bind to?

A

nuclear receptor

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15
Q

what conditions should thyroid function be considered in?

A
AF
hyperlipidaemia
DM
amiodarone
lithium
Down's 
Turner's
Addison's
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16
Q

what else to consider in low T3/4

A

problems with conversion e.g. deiodinase deficiency

changes in TBG

17
Q

diffuse goitre causes

A

physiological
Grave’s
Hashimoto’s
DeQuervain’s

18
Q

nodular goitre causes

A

multinodular goitre
adenoma
carcinoma

19
Q

when to recheck in sub-clinical thyroid?

A

2-4 months
if no symptoms then 6 months
may be worth checking antibodies to prevent progression to myxoedema coma and thyroid storm

20
Q

drug causes of hyperparathyroidism

A

lithium

thiazides