T2DM Flashcards
1
Q
what is T2DM
A
progressive loss of insulin secretion with insulin resistance
2
Q
causes of T2DM
A
environment
genetically vulnerable beta cells
3
Q
which type of diabetes is family history more important in?
A
T2
4
Q
presentation of T2DM
A
insidious onset polyuria polydipsia UTIs malaise
5
Q
who gets T2DM
A
often middle-aged/elderly
obese
6
Q
diagnosis of T2DM
A
2 abnormal results of:
- random blood glucose
- fasting blood glucose (75g anhydrous glucose in water)
7
Q
fasting glucose for diabetes
A
> 7.0mmol/L
8
Q
fasting glucose for pre-diabetes
A
6.1-6.9mmol/L
9
Q
2 hour glucose in OGTT diabetes result
A
> 11.1mmol/L
10
Q
2 hour glucose in OGTT pre-diabetes result
A
7.8-11.0mmol/L
11
Q
random glucose diabetes result
A
> 11.1mmol/L
12
Q
HbA1c in diabetes
A
> 48m/m
pre-diabetes is 42-47m/m
13
Q
who should diabetes testing be considered in?
A
overweight first degree relative high risk ethnicity CVD/hypertension hypercholesteremia PCOS
14
Q
management of T2DM
A
lifestyle e.g. diet, exercise
HbA1c control (<53/48)
pharmacological options
15
Q
pharmacological options
A
- metformin
- SUs or TZDs or DPP4i or SGLT2i
- insulin
