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MRCS > Thyroid and breast > Flashcards

Thyroid and breast Flashcards

1
Q

Histological finding for Papillary carcinoma

A

Psammoma bodies and orphan Annie nuclei

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2
Q

What is the metastatic spread of papillary carcinoma?

A

Lymphatic spread

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3
Q

Macroscopic finding of Follicular carcinoma

A

Well encapsulated invasion on microscopic evaluation

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4
Q

What is the metastatic spread of follicular carcinoma?

A

Haematogenous spread (can include bone)

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5
Q

Who is anaplastic carcinoma most commonly seen in

A

Elderly females

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6
Q

Which cells of origin is medullary carcinoma

A

Parafollicular (C Cells) - of the thyroid

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7
Q

In medullary carcinoma what is serum calcitonin?

A

Elevated

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8
Q

Metastatic spread of medullary carcinoma?

A

Both lymph and haematogenous

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9
Q

Which malignancy are you risk of developing with autoimmune thyroiditis

A

Thyroid lymphoma

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10
Q

Which thyroid cancer is associated with phaeochromocytoma?

A

medullary thyroid cancer

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11
Q

Which is the most common subtype of thyroid cancer?

A

Papillary carcinoma

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12
Q

Which thyroid cancer is included in MENIIa and IIb?

A

Medullary thyroid cancer

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13
Q

Which blood test is useful to screen for papillary carcinoma recurrence?

A

Thyroglobulin levels

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14
Q

What is berry sign?

A

Absence of carotid pulse due to malignant thyromegally

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15
Q

What is CD20 a marker for?

A

B cell lymphoma (thyroid)

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16
Q

What is seen histologically in lymphoma?

A

dense lymphatic tissue

17
Q

Lymphocytic infiltrates and fibrosis are seen in which disease?

A

hashimotos thyroiditis

18
Q

What makes up psammoma bodies seen in papillary lesions?

A

Dystrophic calcification

19
Q

What makes up a fibroadenoma?

A

Stromal and epithelial components

20
Q

Which medication is used in breast cancer for oestrogen sensitive breast cancer?

A

Tamoxifen pre menopausal, letrozole post menopausal

21
Q

which immunoglobulin is involved in graves?

A

IgG

22
Q

Which antibodies are involved in hashimotos thyroiditis?

A

antithyroglobulin and anti microsomal antibodies

23
Q

What is produced by the anterior pituitary?

A

GH, ACTH, TSH, FSH and LH

24
Q

What is produced by the posterior pituitary?

A

ADH and oxytocin

25
Q

What is a rapidly growing breast tumour?

A

Phyllodes tumour

MRCS (19 decks)

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