Thyroid Flashcards
In a study of 13 dogs with thyroid tumors using palliative RT, dogs that had tumor growth greater than 5% per week prior to RT…
had decreased survival
10 versus 30 months
In a study of 13 dogs with thyroid tumors using palliative RT, what % had pulmonary mets?
38% had pulmonary mets at time of tx
In a study of 13 dogs with thyroid tumors using palliative RT, what percentage of dogs were hypothyroid and what percentage were hypoparathyroid after RT?
8-15% hypothyroid
8% hypoparathyroid
In a study of 25 dogs with thyroid tumors treated with DRT the time to maximum tumor reduction was how many months?
8-22 mos
Tumors slow to decrease in size
In a study of 25 dogs with thyroid tumors treated with DRT, dogs with bilateral tumors had what times risk of mets over unilateral tumors?
16 times
In a study of 25 dogs treated for thyroid tumors with DRT, dogs without tumor progression had what times decreased risk of mets?
15
In a study of 8 dogs with thyroid tumors treated with DRT, what percentage had lymph node mets at time of treatment?
50%
In general what percentage of dogs with thyroid tumors have metastatic disease at diagnosis, and what percentage develop metastatic disease?
35-40%
80%
What is the relationship between increase metastatic potential of thyroid tumors and tumor volume in dogs?
tumors < 23 cm3 = 20% mets
tumors >23 cm3 = 70% mets
tumors >100 cm3 = 100% mets
In general, canine bilateral thyroid tumors are what times more likely to metastasize than unilateral tumors?
16
What are the relative percentages of functional levels of thyroid tumors in dogs?
60% euthyroid
30% hypothyroid
10% hyperthyroid
Regarding I131 therapy for thyroid tumors in dogs, what is the difference in MST for euthyroid, hypothyroid, and hyperthyroid dogs?
They are all similar.
Do dogs treated with I-131 for thyroid tumors require thyroid hormone supplementation after therapy?
Yes
In a 2006 article evaluating CD31 and factor 8 for MVD staining, what was found regarding thyroid carcinomas?
MVD was increased incarcinomas but did not correlate with prognosis
Regarding feline hyperthyroidism what percentage of cats have multi-nodular adenomatous hyperplasia?
75%
