Thymus Gland (Exam 1) Flashcards
What does the lymphatic system consist of?
-lymphatic vessels
-immune system cells
-lymphoid tissues and organs
-immunosurveilence and defense
What are the lymphatic vessels?
A) capillaries
B) collecting vessels
C) regional trunks
C1) jugular
C2) subclavian
C3) bronchi-mediastinal
C4) R/L lumbar
C5) intestinal
D) ducts
D1) R lymphatic
D2) L thoracic
What does the R lymphatic duct drain?
R 1/2 of head and R side of thorax and R arm
What does the L thoracic duct drain?
Everything that R lymphatic duct doesn’t drain
R lymphatic duct drains R 1/2 of head, R trunk, and R arm
The L thoracic duct and R lymphatic duct drain into the ___________________ on that side
Subclavian v.
So L thoracic duct drains into L subclavian and R lymphatic duct drains into R subclavian v.
The thymus gland is a lymphatic organ that is located deep to the sternum and undergoes ______________.
Test q
involution
Thymocytes migrate here to become mature T cells
Test q
Thymus gland
The thymus gland secretes…..
Test q
Thymic hormones
What are thymocytes?
-T cell precursors derived from hematopoietic stem cells in BM
-thymocytes migrate to the thymus via the blood stream where they mature into T lymphocytes
T cell maturation involves _____________________- becoming functional for attack against specific pathogens
immunocompetency
The thymus gland is __________ and the lobes divide into lobules which are separated by CT (trabeculae). The lobules consist of a cortex and medulla. The cortex has rapidly dividing _____________ that are densely packed. The medulla has less cells, but it does have some thymic (Hassall’s) corpuscles
Bilobed, thymocytes
The ____________________ are whorls of reticular epithelial cells that destroy defective T cells capable of attacking the body’s own cells. This prevents autoimmune disease
Hassall corpuscles
What are the 4 cell types of the thymus gland?
1) stromal cells
2) reticular epithelial cells
3) adipose cells
4) thymocytes
Where are stromal cells found?
Within CT and blood vessels of organs
Which cells produce thymus hormones?
Test q
Reticular epithelial cells