THROYID Flashcards

1
Q
1. Characteristic findings in subclinical hyperthyroidism, except:
Select one:
a. normal Se FT3
b. anti-TPO Ab is not typical
c. normal Se FT4
d. Se FT4 ↓ and normal FT3
e. Se TSH ↓
A

d

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2
Q
2. Increased radioactive iodine intake in thyroid gland:
Select one or more:
a. iodine deficiency
b. Hashimoto’s thyroiditis
c. toxic adenoma
d. thyrotoxicosis factitia
A

a/c

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3
Q
3. How much of the circulating T4 is free?
Select one:
a. 5-10 %
b. 20-50 %
c. 0.01-0.05%
d. 1-3 %
e. 0.1-0.3 %
A

c

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4
Q
5. Thyroid nodule is rather benign, if:
19
Pathophysiology 1 MCQs - Team effort
Select one or more:
a. thyroid scintigraphy shows a cold nodule
b. thyroid antibody titer is elevated
c. develops in young men
d. it is soft to touch
A

d

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5
Q
6. Possible cause of hyperthyroidism, except:
Select one:
a. iodine deficiency
b. Hashimoto’s thyroiditis
c. struma ovarii
d. thyrotoxicosis factitia
e. Sub acute thyroiditis
A

a

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6
Q
7. Incidence of hypothyroidism in the population:
Select one:
a. 20-30%
b. 0.1-0.5 %
c. 30-40 %
d. 3-5 %
e. 10-20 %
A

d

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7
Q
8. Clinical signs of hypothyroidism:
Select one or more:
a. pretibial myxedema
b. anemia
c. hypertriglyceridemia
d. Carotinoderma
A

b/c/d

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8
Q
9. The most common causes of euthyroid goiter:
Select one or more:
a. subacute thyroiditis
20
Pathophysiology 1 MCQs - Team effort
b. Plummer’s disease
c. congenital T4 receptor deficiency
d. struma ovarii
A

a/c

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9
Q
10. High risk groups for hypothyroidism:
Select one or more:
a. women
b. type 1 DM
c. age between 45-65
d. patients with Graves-Basedow disease or postpartum thyroidal dysfunction in the anamnesis
A

a/b/c/d

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10
Q
  1. True statements for subacute thyroiditis:
    Select one or more:
    a. RAIU increased
    b. symptoms include fever and thyroid tenderness
    c. it is probably due to a viral infection
    d. always causes hypothyroidism
A

b/c

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11
Q
12. Observations in iodine deficiency:
Select one:
a. RAIU ↓
b. Se FT4 ↓, and FT3 ↑
c. Se TSH ↓
d. Se FT4 ↑ and FT3 ↑
e. Se FT4 ↑ and FT3
A

b

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12
Q
13. Possible causes of euthyroid goiter:
Select one or more:
a. Hashimoto’s thyroiditis
b. Graves-Basedow disease
c. iodine deficiency
d. subacute thyroiditis
A

a/c/d

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13
Q
  1. Possible cause of primary hypothyroidism:
    Select one or more:
    a. irradiation (radioactive iodine therapy of hyperthyroidism)
    b. lithium therapy
    c. Hashimoto’s thyroiditis
    d. Plummer’s disease
A

a/b/c

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14
Q
15. Possible cause of euthyroid goiter, except:
Select one:
a. subacute thyroiditis
b. iodine deficiency
c. Hashimoto’s thyroiditis
d. excessive consumption of brassica
e. Graves-Basedow disease
A

e

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15
Q
  1. False statement for subacute thyroiditis:
    Select one:
    a.fever, pain
    b. absence of anti-thyroidal antibodies
    c. viral infection is involved in the etiology
    d. increased RAIU
    e. enlargement of thyroid gland
A

d

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16
Q
17. Clinical signs of hypothyroidism, except:
Select one:
a. carotinoderma
b. tachycardia
c. myxedema
d. constipation
e. Anemia
A

b

17
Q
18. Approximate weight of the thyroid gland:
22
Pathophysiology 1 MCQs - Team effort
Select one:
a. 100-150 g
b. 25-30 g
c. 250-300 g
d. 25-30 mg
e. 1-3 g
A

b

18
Q
  1. Characteristic findings in Hashimoto’s thyroiditis, except:
    Select one:
    a. hyperthyroidism is observed usually at the beginning of the disease
    b. enlarged multinodular goiter
    c. histologically lymphocytic/plasmacytic infiltration in the thyroid gland
    d. genetically transmitted
    e. more common in women
A

b

19
Q
  1. True statement for Hashimoto’s thyroiditis:
    Select one or more:
    a. often occurs together with type 1 DM
    b. anti-Tg Ab usually negative
    c. anti-TPO Ab often increased significantly
    d. patients usually have painless goiter
A

a/c/d

20
Q
21.Typical clinical findings in Graves-Besedow disease:
Select one or more:
a. fatigue
b. euthyreoid goiter
c. HLA-B8 and DR3 association
d. Atrial fibrillation
A

a/c/d

21
Q
22. Possible cause of hyperthyroidism:
Select one or more:
a. subacute thyroiditis
b. struma ovarii
c. toxic uninodular or multinodular goiter
d. toxic diffuse goiter
A

a/b/c/d

22
Q
23. Which parameter is not altered in Graves-Basedow’s disease?
Select one:
a. thyroglobulin (Tg)
b. Se FT4
c. anti-TPO Ab
d. anti-TR Ab
e. RAIU
A

a

23
Q
24. Possible cause of hypothyroidism, except:
Select one:
a. increased iodine uptake
b. iodine deficiency
c. subacute thyroiditis
d. Hashimoto’s thyroiditis
e. Graves-Basedow disease
A

e

24
Q
25. Effects of TSH, except:
Select one:
a. increases the mass of thyroid gland
b. potentiate the release of TRH
c. increases the vascularization of thyroid gland
d. increases iodine uptake
e. increases the synthesis of T4/T3
A

b

25
Q
26. Characteristic findings in toxic adenoma (Plummer’s disease), except:
Select one:
a. more frequent in women
b. exophthalmus
c. hyperthyroidism
d. Se TSH ↓
e. Goiter
A

b/c/d

26
Q
27. Clinical signs of hyperthyroidism:
Select one or more:
a. abnormal menstrual cycles
b. bradycardia
c. von Graefe’s sign
d. hoarseness
A

a/c/d

27
Q
  1. Effects of TSH:
    Select one or more:
    a. increase the size of thyroid gland
    b. reduces the vascularization of thyroid gland
    c. increase the synthesis and release of T4 / T3 via Ca2+-intracellular signaling
    d. enhance iodine uptake
A

a/d

28
Q
  1. False statements for postpartum thyroiditis:
    a. may cause hyper- or hypothyroidism, as well
    b. the presence of anti-TPO Ab and/or anti-TG Ab indicate the development of permanent hypothyroidism.
    c. a type of Hashimoto’s thyroiditis that develops in pregnancy.
    d. lymphocytic thyroiditis.
    e. observed following pregnancy.
A

c

29
Q
30. Clinical signs of hypermyroidism:
Select one or more:
a. hoarseness
b. abnormal menstrual cycles
c. bradycardia
d. von Graefe's sign
A

a/b/d