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pituitary gonad Flashcards

1
Q
  1. Characteristic finding in Pygmy dwarfism
    Select one:
    a. complete lack of IGF-II
    b. failure of IGF-I to increase at puberty
    c. extreme short stature (<120 cm)
    d. reduced serum GH level
    e. IGF-I receptor deficiency
A

b

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2
Q 
2. Formed in the frontal lobe of hypophysis, except:
Select one:
a. LH
b. TSH
c. prolactin
d. oxytocin
e. GH
A

d

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3
Q 
3. Sheehan’s syndrome may develop, due to:
Select one:
a. adenoma
b. brain edema
c. infection
d. hypophysectomy
e. increased blood loss at birth
A

e

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4
Q 
4. Corticotropin-related peptides, except:
Select one:
a. MSH
b. LPH
c. endorphins

d. ACTH
e. Prolactin
6. Loss of pituitary fun

A

e

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5
Q 
6. Loss of pituitary function develops due to, except:
Select one:
a. aplasia
b. craniopharyngeoma
c. iatrogenic
d. Addison’s disease
e. Adenoma
A

d

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6
Q 
7. Tropic hormones, except:
Select one:
a. TSH
b. FSH
c. LPH
d. LH
E. ACTH
A

c

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7
Q 
8. Clinical signs of androgen excess in women:
Select one or more:
a. gynecomastia
b. hirsutism
c. alopecia
d. hypertension
A

b/c/d

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8
Q 
9. Causes of secondary amenorrhea:
Select one or more:
a. prolactinoma
b. Kallmann syndrome
c. pregnancy
d. artificial abortion
A

a/c

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9
Q 
9. Causes of secondary amenorrhea:
Select one or more:
a. prolactinoma
b. Kallmann syndrome
c. pregnancy
d. artificial abortion
A

A/C

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10
Q 
10. Clinical symptoms of acromegaly:
Select one or more:
a. hypogonadism
b. hyperostosis
c. cardiomegaly
d. barrel chest
A

A/B/C/D

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11
Q 
11. Most common causes of hypertrichosis:
Select one or more:
a. polycystic ovary syndrome
b. paraneoplastic syndrome
c. hypothyroidism
d. Klinefelter syndrome
A

B/C

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12
Q
  1. True statements for Klinefelter syndrome:
    Select one or more:
    a. the most common cause of primary hypogonadism
    b. tall stature
    c. breast cancer often develops
    d. karyotype: XX0
A

a/c/b

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13
Q 
13. May indicate polycystic ovary syndrome:
Select one or more:
a. dyslipidemia
b. oligomenorrhea
c. weight loss
d. IGT / IFG
A

a/b/d

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14
Q
  1. False statement for dwarfism:
    Select one:
    a. connective tissue disorders can also cause
    b. the most common cause is achondroplasia formed as a result of FGF R3 mutation
    59
    Pathophysiology 1 MCQs - Team effort
    c. adult height < 147 cm
    d. can develop even with an increased secretion of GH
    e. Se GH-level is always low
A

e

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15
Q 
15. First symptom of Sheehan-syndrome could be:
Select one:
a. impotence
b. vitiligo
c. loss of pubic hair
d. anemia
e. failure of lactation
A

e

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16
Q 
16. Clinical signs of growth hormone deficiency, except:
Select one:
a. growth retardation (in childhood)
b. decreased BMD
c. Se HDL↑
d. muscle weakness
e. central obesity
A

c

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17
Q
  1. Typical features of Laron-dwarfs, except:
    Select one:
    a. decreased Se IGF-I
    b. GH secretion cannot be inhibited with glucose
    c. hereditary disorder
    d. decreased Se GH
    e. extreme short stature
A

d

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18
Q 
8. Characteristic signs of acromegaly, except:
Select one or more:
a. obesity
b. macroglossia
60
Pathophysiology 1 MCQs - Team effort
c. tall stature
d. prognathism
A

a/c

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19
Q 
19. Causes of SIADH:
Select one or more:
a. myocardial infarct
b. pneumonia
c. small cell carcinoma of the lung
d. subarachnoid bleeding
A

b/c/d

20
Q 
20. Characteristic signs of diabetes insipidus, except:
Select one or more:
a. nycturia or nocturnal enuresis
b. polyuria, polydipsia, thirst
c. hyperhidrosis
d. hyponatremic dehydration
A

c/d

21
Q 
21. Risk factors of endometriosis:
Select one or more:
a. early menarche
b. long menstrual cycle
c. smoking
d. alcohol consumption
A

a/d

22
Q
  1. Possible cause of pseudohermaphroditism in men:
    Select one or more:
    a. testicular feminization
    b. failure of secretion of testosterone or Müllerian duct inhibitory factors
    c. failure of conversion of testosterone to DHT
    d. Turner syndrome
A

b/c

23
Q 
23. Causes of acromegaly:
Select one or more:
a. pituitary adenoma
b. Cushing-disease
c. paraneoplastic syndrome
d. McCune–Albright syndrome
A

a/c

24
Q 
24. Clinical signs of endometriosis:
Select one or more:
a. hirsutisms
61
Pathophysiology 1 MCQs - Team effort
b. dyspareunia
c. infertility
d. Dys menorrhea
A

b/c/d

25
Q 
25. The most frequent cause of nanosomia:
Select one:
a. connective tissue diseases
b. hypothyroidism
c. achondroplasia
d. GH-related disorders
e. psychogenic causes
A

c

26
Q 
26. Cause of nanosomia, except:
Select one:
a. achondroplasia
b. McCune–Albright syndrome
c. Turner syndrome
d. hypothyroidism
e. osteogenesis imperfecta
A

b

27
Q 
27. Clinical signs of polycystic ovary syndrome:
Select one or more:
a. hirsutisms
b. amenorrhea
c. acne
d. smaller ovaries
A

a/c

28
Q 
28. Clinical manifestations of prolactinoma in men:
Select one or more:
a. hirsutism
b. virilization
c. headache
d. Gynecomastia
A

c/d

29
Q
  1. Effects of ADH:
    Select one or more:
    a. Vasoconstriction
    b. Enhances reabsorption of urea increasing tonicity of the renal medulla allowing more water to be
    re-absorbed
    62
    Pathophysiology 1 MCQs - Team effort
    c. During hypovolemia high plasma levels of AVP help maintain tissue perfusion
    d. Stimulates the synthesis and release of factor VIII and von-Willebrand factor via V2 non-renal receptors
A

a/b/c

30
Q 
30. Causes of precocious puberty can be:
Select one or more:
a. regular use of marijuana
b. hCG-secreting tumor
c. congenital adrenal hyperplasia
d. McCune–Albright syndrome
A

a/b/c/b/

31
Q 
31. Which of the following diseases can cause hirsutism?
Select one or more:
a. hyperparathyreosis
b. Cushing’s syndrome
c. congenital adrenal hyperplasia
d. polycystic ovary syndrome
A

b/c/d

32
Q 
32. Cause of nanosomia, except:
Hirsutism can be caused by:
Select one or more:
a. hypothyroidism
b. Cushing’s syndrome
c. polycystic ovary syndrome
d. Klinefelter syndrome
A

b/c

33
Q 
33. Which pituitary hormone level will decrease first due to a progressive loss of pituitary function?
Select one:
a. LH
b. ADH
c. TSH
d. ACTH
e. Prolactin
A

a

34
Q 
34. ADH release is stimulated by:
Select one or more:
a. histamine
b. emotional factors and stress
c. plasma osmolality > 280 mosm/l
d. Sleep
A

a/b/c/d

35
Q 
35. Causes of primary amenorrhea:
Select one or more:
a. Kallmann syndrome
b. chromosomal abnormality
c. Müllerian duct agenesis
d. anorexia nervosa
A

a/b/c/d

36
Q 
36. The following hormones synthetized by adenohypophysis, except
Select one or more:
a. GH
b. ADH
c. TSH
d. GnRH
A

b/d

37
Q 
37. Clinical signs of prolactinoma:
Select one or more:
a. infertility
b. hypertension
c. primary or secondary amenorrhea
d. decreased libido
A

a/c/d

38
Q 
38. Glycoprotein hormones, except:
64
Pathophysiology 1 MCQs - Team effort
Select one:
a. testosterone
b. FSH
c. LH
d. hCG
e. TSH
A

a

39
Q 
39. Hypothalamic hormones, except:
Select one:
a. GnRH
b. hCG
c. Vasopressin
d. CRH
e. TRH
A

b

40
Q 
40. Clinical manifestation of prolactinoma in women, except:
Select one or more:
a. hirsutisms
b. amenorrhea
c. gynecomastia
d. Headache
A

c

41
Q 
41. Causes of primary hypogonadism:
Select one or more:
a. mumps viral infection
b. Klinefelter syndrome
c. seminoma
d. Cryptorchidism
A

b/d

42
Q 
42. Correct statements for Laron dwarfism:
Select one or more:
a. the incidence of malignancy and DM is increased in these patients
65
Pathophysiology 1 MCQs - Team effort
b. GH receptor defect
c. extreme short (<120 cm) stature
d. GH secretion is suppressed by glucose
A

b/c

43
Q 
43. Clinical manifestation of prolactinoma in women:
Select one or more:
a. gynecomastia
b. amenorrhea
c. hirsutism
d. virilization
A

b/c

44
Q 
45. Possible causes of gynecomastia:
Select one or more:
a. cirrhosis of the liver
b. hyperthyroidism
c. 11b-hydroxylase deficiency
d. puberty
A

a

45
Q 
47. Characteristic laboratory findings in polycystic ovary syndrome:
Select one or more:
a. Se testosterone↑
b. Se prolactin↓
c. Se SHBG ↓
d. Se insulin ↓
A

a/c

46
Q 
48. Characteristic laboratory findings in polycystic ovary syndrome:
Select one or more:
a. Se estrogen↑
b. Se insulin ↓
c. Se FSH↑
d. Se LH↑
A

a/d

pathophys (17 decks)

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