pituitary gonad Flashcards
1
Q
- Characteristic finding in Pygmy dwarfism
Select one:
a. complete lack of IGF-II
b. failure of IGF-I to increase at puberty
c. extreme short stature (<120 cm)
d. reduced serum GH level
e. IGF-I receptor deficiency
A
b
2
Q
2. Formed in the frontal lobe of hypophysis, except: Select one: a. LH b. TSH c. prolactin d. oxytocin e. GH
A
d
3
Q
3. Sheehan’s syndrome may develop, due to: Select one: a. adenoma b. brain edema c. infection d. hypophysectomy e. increased blood loss at birth
A
e
4
Q
4. Corticotropin-related peptides, except: Select one: a. MSH b. LPH c. endorphins
d. ACTH
e. Prolactin
6. Loss of pituitary fun
A
e
5
Q
6. Loss of pituitary function develops due to, except: Select one: a. aplasia b. craniopharyngeoma c. iatrogenic d. Addison’s disease e. Adenoma
A
d
6
Q
7. Tropic hormones, except: Select one: a. TSH b. FSH c. LPH d. LH E. ACTH
A
c
7
Q
8. Clinical signs of androgen excess in women: Select one or more: a. gynecomastia b. hirsutism c. alopecia d. hypertension
A
b/c/d
8
Q
9. Causes of secondary amenorrhea: Select one or more: a. prolactinoma b. Kallmann syndrome c. pregnancy d. artificial abortion
A
a/c
9
Q
9. Causes of secondary amenorrhea: Select one or more: a. prolactinoma b. Kallmann syndrome c. pregnancy d. artificial abortion
A
A/C
10
Q
10. Clinical symptoms of acromegaly: Select one or more: a. hypogonadism b. hyperostosis c. cardiomegaly d. barrel chest
A
A/B/C/D
11
Q
11. Most common causes of hypertrichosis: Select one or more: a. polycystic ovary syndrome b. paraneoplastic syndrome c. hypothyroidism d. Klinefelter syndrome
A
B/C
12
Q
- True statements for Klinefelter syndrome:
Select one or more:
a. the most common cause of primary hypogonadism
b. tall stature
c. breast cancer often develops
d. karyotype: XX0
A
a/c/b
13
Q
13. May indicate polycystic ovary syndrome: Select one or more: a. dyslipidemia b. oligomenorrhea c. weight loss d. IGT / IFG
A
a/b/d
14
Q
- False statement for dwarfism:
Select one:
a. connective tissue disorders can also cause
b. the most common cause is achondroplasia formed as a result of FGF R3 mutation
59
Pathophysiology 1 MCQs - Team effort
c. adult height < 147 cm
d. can develop even with an increased secretion of GH
e. Se GH-level is always low
A
e
15
Q
15. First symptom of Sheehan-syndrome could be: Select one: a. impotence b. vitiligo c. loss of pubic hair d. anemia e. failure of lactation
A
e
16
Q
16. Clinical signs of growth hormone deficiency, except: Select one: a. growth retardation (in childhood) b. decreased BMD c. Se HDL↑ d. muscle weakness e. central obesity
A
c
17
Q
- Typical features of Laron-dwarfs, except:
Select one:
a. decreased Se IGF-I
b. GH secretion cannot be inhibited with glucose
c. hereditary disorder
d. decreased Se GH
e. extreme short stature
A
d
18
Q
8. Characteristic signs of acromegaly, except: Select one or more: a. obesity b. macroglossia 60 Pathophysiology 1 MCQs - Team effort c. tall stature d. prognathism
A
a/c
19
Q
19. Causes of SIADH: Select one or more: a. myocardial infarct b. pneumonia c. small cell carcinoma of the lung d. subarachnoid bleeding
A
b/c/d
20
Q
20. Characteristic signs of diabetes insipidus, except: Select one or more: a. nycturia or nocturnal enuresis b. polyuria, polydipsia, thirst c. hyperhidrosis d. hyponatremic dehydration
A
c/d
21
Q
21. Risk factors of endometriosis: Select one or more: a. early menarche b. long menstrual cycle c. smoking d. alcohol consumption
A
a/d
22
Q
- Possible cause of pseudohermaphroditism in men:
Select one or more:
a. testicular feminization
b. failure of secretion of testosterone or Müllerian duct inhibitory factors
c. failure of conversion of testosterone to DHT
d. Turner syndrome
A
b/c
23
Q
23. Causes of acromegaly: Select one or more: a. pituitary adenoma b. Cushing-disease c. paraneoplastic syndrome d. McCune–Albright syndrome
A
a/c
24
Q
24. Clinical signs of endometriosis: Select one or more: a. hirsutisms 61 Pathophysiology 1 MCQs - Team effort b. dyspareunia c. infertility d. Dys menorrhea
A
b/c/d
25
Q
25. The most frequent cause of nanosomia: Select one: a. connective tissue diseases b. hypothyroidism c. achondroplasia d. GH-related disorders e. psychogenic causes
A
c
26
Q
26. Cause of nanosomia, except: Select one: a. achondroplasia b. McCune–Albright syndrome c. Turner syndrome d. hypothyroidism e. osteogenesis imperfecta
A
b
27
Q
27. Clinical signs of polycystic ovary syndrome: Select one or more: a. hirsutisms b. amenorrhea c. acne d. smaller ovaries
A
a/c
28
Q
28. Clinical manifestations of prolactinoma in men: Select one or more: a. hirsutism b. virilization c. headache d. Gynecomastia
A
c/d
29
Q
- Effects of ADH:
Select one or more:
a. Vasoconstriction
b. Enhances reabsorption of urea increasing tonicity of the renal medulla allowing more water to be
re-absorbed
62
Pathophysiology 1 MCQs - Team effort
c. During hypovolemia high plasma levels of AVP help maintain tissue perfusion
d. Stimulates the synthesis and release of factor VIII and von-Willebrand factor via V2 non-renal receptors
A
a/b/c
30
Q
30. Causes of precocious puberty can be: Select one or more: a. regular use of marijuana b. hCG-secreting tumor c. congenital adrenal hyperplasia d. McCune–Albright syndrome
A
a/b/c/b/
31
Q
31. Which of the following diseases can cause hirsutism? Select one or more: a. hyperparathyreosis b. Cushing’s syndrome c. congenital adrenal hyperplasia d. polycystic ovary syndrome
A
b/c/d
32
Q
32. Cause of nanosomia, except: Hirsutism can be caused by: Select one or more: a. hypothyroidism b. Cushing’s syndrome c. polycystic ovary syndrome d. Klinefelter syndrome
A
b/c
33
Q
33. Which pituitary hormone level will decrease first due to a progressive loss of pituitary function? Select one: a. LH b. ADH c. TSH d. ACTH e. Prolactin
A
a
34
Q
34. ADH release is stimulated by: Select one or more: a. histamine b. emotional factors and stress c. plasma osmolality > 280 mosm/l d. Sleep
A
a/b/c/d
35
Q
35. Causes of primary amenorrhea: Select one or more: a. Kallmann syndrome b. chromosomal abnormality c. Müllerian duct agenesis d. anorexia nervosa
A
a/b/c/d
36
Q
36. The following hormones synthetized by adenohypophysis, except Select one or more: a. GH b. ADH c. TSH d. GnRH
A
b/d
37
Q
37. Clinical signs of prolactinoma: Select one or more: a. infertility b. hypertension c. primary or secondary amenorrhea d. decreased libido
A
a/c/d
38
Q
38. Glycoprotein hormones, except: 64 Pathophysiology 1 MCQs - Team effort Select one: a. testosterone b. FSH c. LH d. hCG e. TSH
A
a
39
Q
39. Hypothalamic hormones, except: Select one: a. GnRH b. hCG c. Vasopressin d. CRH e. TRH
A
b
40
Q
40. Clinical manifestation of prolactinoma in women, except: Select one or more: a. hirsutisms b. amenorrhea c. gynecomastia d. Headache
A
c
41
Q
41. Causes of primary hypogonadism: Select one or more: a. mumps viral infection b. Klinefelter syndrome c. seminoma d. Cryptorchidism
A
b/d
42
Q
42. Correct statements for Laron dwarfism: Select one or more: a. the incidence of malignancy and DM is increased in these patients 65 Pathophysiology 1 MCQs - Team effort b. GH receptor defect c. extreme short (<120 cm) stature d. GH secretion is suppressed by glucose
A
b/c
43
Q
43. Clinical manifestation of prolactinoma in women: Select one or more: a. gynecomastia b. amenorrhea c. hirsutism d. virilization
A
b/c
44
Q
45. Possible causes of gynecomastia: Select one or more: a. cirrhosis of the liver b. hyperthyroidism c. 11b-hydroxylase deficiency d. puberty
A
a
45
Q
47. Characteristic laboratory findings in polycystic ovary syndrome: Select one or more: a. Se testosterone↑ b. Se prolactin↓ c. Se SHBG ↓ d. Se insulin ↓
A
a/c
46
Q
48. Characteristic laboratory findings in polycystic ovary syndrome: Select one or more: a. Se estrogen↑ b. Se insulin ↓ c. Se FSH↑ d. Se LH↑
A
a/d
