pituitary gonad Flashcards
1
Q
- Characteristic finding in Pygmy dwarfism
Select one:
a. complete lack of IGF-II
b. failure of IGF-I to increase at puberty
c. extreme short stature (<120 cm)
d. reduced serum GH level
e. IGF-I receptor deficiency
A
b
2
Q
2. Formed in the frontal lobe of hypophysis, except: Select one: a. LH b. TSH c. prolactin d. oxytocin e. GH
A
d
3
Q
3. Sheehan’s syndrome may develop, due to: Select one: a. adenoma b. brain edema c. infection d. hypophysectomy e. increased blood loss at birth
A
e
4
Q
4. Corticotropin-related peptides, except: Select one: a. MSH b. LPH c. endorphins
d. ACTH
e. Prolactin
6. Loss of pituitary fun
A
e
5
Q
6. Loss of pituitary function develops due to, except: Select one: a. aplasia b. craniopharyngeoma c. iatrogenic d. Addison’s disease e. Adenoma
A
d
6
Q
7. Tropic hormones, except: Select one: a. TSH b. FSH c. LPH d. LH E. ACTH
A
c
7
Q
8. Clinical signs of androgen excess in women: Select one or more: a. gynecomastia b. hirsutism c. alopecia d. hypertension
A
b/c/d
8
Q
9. Causes of secondary amenorrhea: Select one or more: a. prolactinoma b. Kallmann syndrome c. pregnancy d. artificial abortion
A
a/c
9
Q
9. Causes of secondary amenorrhea: Select one or more: a. prolactinoma b. Kallmann syndrome c. pregnancy d. artificial abortion
A
A/C
10
Q
10. Clinical symptoms of acromegaly: Select one or more: a. hypogonadism b. hyperostosis c. cardiomegaly d. barrel chest
A
A/B/C/D
11
Q
11. Most common causes of hypertrichosis: Select one or more: a. polycystic ovary syndrome b. paraneoplastic syndrome c. hypothyroidism d. Klinefelter syndrome
A
B/C
12
Q
- True statements for Klinefelter syndrome:
Select one or more:
a. the most common cause of primary hypogonadism
b. tall stature
c. breast cancer often develops
d. karyotype: XX0
A
a/c/b
13
Q
13. May indicate polycystic ovary syndrome: Select one or more: a. dyslipidemia b. oligomenorrhea c. weight loss d. IGT / IFG
A
a/b/d
14
Q
- False statement for dwarfism:
Select one:
a. connective tissue disorders can also cause
b. the most common cause is achondroplasia formed as a result of FGF R3 mutation
59
Pathophysiology 1 MCQs - Team effort
c. adult height < 147 cm
d. can develop even with an increased secretion of GH
e. Se GH-level is always low
A
e
15
Q
15. First symptom of Sheehan-syndrome could be: Select one: a. impotence b. vitiligo c. loss of pubic hair d. anemia e. failure of lactation
A
e
16
Q
16. Clinical signs of growth hormone deficiency, except: Select one: a. growth retardation (in childhood) b. decreased BMD c. Se HDL↑ d. muscle weakness e. central obesity
A
c
17
Q
- Typical features of Laron-dwarfs, except:
Select one:
a. decreased Se IGF-I
b. GH secretion cannot be inhibited with glucose
c. hereditary disorder
d. decreased Se GH
e. extreme short stature
A
d
18
Q
8. Characteristic signs of acromegaly, except: Select one or more: a. obesity b. macroglossia 60 Pathophysiology 1 MCQs - Team effort c. tall stature d. prognathism
A
a/c
19
Q
19. Causes of SIADH: Select one or more: a. myocardial infarct b. pneumonia c. small cell carcinoma of the lung d. subarachnoid bleeding
A
b/c/d
20
Q
20. Characteristic signs of diabetes insipidus, except: Select one or more: a. nycturia or nocturnal enuresis b. polyuria, polydipsia, thirst c. hyperhidrosis d. hyponatremic dehydration
A
c/d
21
Q
21. Risk factors of endometriosis: Select one or more: a. early menarche b. long menstrual cycle c. smoking d. alcohol consumption
A
a/d
22
Q
- Possible cause of pseudohermaphroditism in men:
Select one or more:
a. testicular feminization
b. failure of secretion of testosterone or Müllerian duct inhibitory factors
c. failure of conversion of testosterone to DHT
d. Turner syndrome
A
b/c
23
Q
23. Causes of acromegaly: Select one or more: a. pituitary adenoma b. Cushing-disease c. paraneoplastic syndrome d. McCune–Albright syndrome
A
a/c
24
Q
24. Clinical signs of endometriosis: Select one or more: a. hirsutisms 61 Pathophysiology 1 MCQs - Team effort b. dyspareunia c. infertility d. Dys menorrhea
A
b/c/d
25
```
25. The most frequent cause of nanosomia:
Select one:
a. connective tissue diseases
b. hypothyroidism
c. achondroplasia
d. GH-related disorders
e. psychogenic causes
```
c
26
```
26. Cause of nanosomia, except:
Select one:
a. achondroplasia
b. McCune–Albright syndrome
c. Turner syndrome
d. hypothyroidism
e. osteogenesis imperfecta
```
b
27
```
27. Clinical signs of polycystic ovary syndrome:
Select one or more:
a. hirsutisms
b. amenorrhea
c. acne
d. smaller ovaries
```
a/c
28
```
28. Clinical manifestations of prolactinoma in men:
Select one or more:
a. hirsutism
b. virilization
c. headache
d. Gynecomastia
```
c/d
29
29. Effects of ADH:
Select one or more:
a. Vasoconstriction
b. Enhances reabsorption of urea increasing tonicity of the renal medulla allowing more water to be
re-absorbed
62
Pathophysiology 1 MCQs - Team effort
c. During hypovolemia high plasma levels of AVP help maintain tissue perfusion
d. Stimulates the synthesis and release of factor VIII and von-Willebrand factor via V2 non-renal receptors
a/b/c
30
```
30. Causes of precocious puberty can be:
Select one or more:
a. regular use of marijuana
b. hCG-secreting tumor
c. congenital adrenal hyperplasia
d. McCune–Albright syndrome
```
a/b/c/b/
31
```
31. Which of the following diseases can cause hirsutism?
Select one or more:
a. hyperparathyreosis
b. Cushing’s syndrome
c. congenital adrenal hyperplasia
d. polycystic ovary syndrome
```
b/c/d
32
```
32. Cause of nanosomia, except:
Hirsutism can be caused by:
Select one or more:
a. hypothyroidism
b. Cushing’s syndrome
c. polycystic ovary syndrome
d. Klinefelter syndrome
```
b/c
33
```
33. Which pituitary hormone level will decrease first due to a progressive loss of pituitary function?
Select one:
a. LH
b. ADH
c. TSH
d. ACTH
e. Prolactin
```
a
34
```
34. ADH release is stimulated by:
Select one or more:
a. histamine
b. emotional factors and stress
c. plasma osmolality > 280 mosm/l
d. Sleep
```
a/b/c/d
35
```
35. Causes of primary amenorrhea:
Select one or more:
a. Kallmann syndrome
b. chromosomal abnormality
c. Müllerian duct agenesis
d. anorexia nervosa
```
a/b/c/d
36
```
36. The following hormones synthetized by adenohypophysis, except
Select one or more:
a. GH
b. ADH
c. TSH
d. GnRH
```
b/d
37
```
37. Clinical signs of prolactinoma:
Select one or more:
a. infertility
b. hypertension
c. primary or secondary amenorrhea
d. decreased libido
```
a/c/d
38
```
38. Glycoprotein hormones, except:
64
Pathophysiology 1 MCQs - Team effort
Select one:
a. testosterone
b. FSH
c. LH
d. hCG
e. TSH
```
a
39
```
39. Hypothalamic hormones, except:
Select one:
a. GnRH
b. hCG
c. Vasopressin
d. CRH
e. TRH
```
b
40
```
40. Clinical manifestation of prolactinoma in women, except:
Select one or more:
a. hirsutisms
b. amenorrhea
c. gynecomastia
d. Headache
```
c
41
```
41. Causes of primary hypogonadism:
Select one or more:
a. mumps viral infection
b. Klinefelter syndrome
c. seminoma
d. Cryptorchidism
```
b/d
42
```
42. Correct statements for Laron dwarfism:
Select one or more:
a. the incidence of malignancy and DM is increased in these patients
65
Pathophysiology 1 MCQs - Team effort
b. GH receptor defect
c. extreme short (<120 cm) stature
d. GH secretion is suppressed by glucose
```
b/c
43
```
43. Clinical manifestation of prolactinoma in women:
Select one or more:
a. gynecomastia
b. amenorrhea
c. hirsutism
d. virilization
```
b/c
44
```
45. Possible causes of gynecomastia:
Select one or more:
a. cirrhosis of the liver
b. hyperthyroidism
c. 11b-hydroxylase deficiency
d. puberty
```
a
45
```
47. Characteristic laboratory findings in polycystic ovary syndrome:
Select one or more:
a. Se testosterone↑
b. Se prolactin↓
c. Se SHBG ↓
d. Se insulin ↓
```
a/c
46
```
48. Characteristic laboratory findings in polycystic ovary syndrome:
Select one or more:
a. Se estrogen↑
b. Se insulin ↓
c. Se FSH↑
d. Se LH↑
```
a/d
