adernal Flashcards

1
Q
1. Typical sign of pheochromocytoma, except:
Select one:
a. constipation
b. hypertension developed in paroxysm
c. nausea, vomiting
d. hyperhidrosis
e. 24 hours urine VMA↑
A

a

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2
Q
  1. True statements:
    Select one or more:
    a. glucocorticoids are synthesized in zona glomerulosa
    b. mineralocorticoids are synthesized in zona fasciculata
    c. mineralocorticoids are synthesized in zona glomerulosa
    d. glucocorticoids are synthesized in zona fasciculata
A

c/d

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3
Q
3. Conn-syndrome is not associated with:
Select one:
a. adenoma
b. 21-hydroxylase deficiency
c. 17α-hydroxylase deficiency
d. hyperplasia
e. 11ß-hydroxylase deficiency
A

b

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4
Q
4. Which endocrine disease can cause hypotension?
Select one or more:
a. 21-hydroxylase deficiency
b. Sheehan-syndrome
c. hypothyroidism
d. 11-β-hydroxylase deficienc
A

a/b/c

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5
Q
5. True statements for pheochromocytoma:
Select one or more:
a. extramedullary in 10%
b. malignant in 10%
c. unilateral in 10%
d. acquired in 10%
A

a/b

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6
Q
6. Effects of glucocorticoids:
Select one or more:
a. stimulate bone resorption
b. increase protein synthesis
c. increase gluconeogenesis
d. increase water and Na+-excretion
A

a/c

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7
Q
7. Clinical signs of Cushing-syndrome:
Select one or more:
a. central obesity
b. hypotension
c. virilization
d. psychological disorders
A

a/d

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8
Q
8. Signs of Conn's syndrome:
Select one or more:
a. metabolic acidosis
b. hypertonia
c. hyperkalemia
d. polyuria, polydipsia
A

b/d

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9
Q
9. Clinical signs of pheochromocytoma:
Select one or more:
a. cold limbs
b. sweating
c. headache
d. palpitation
A

a/b/c/d

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10
Q
10. Effects of glucocorticoids, except:
Select one:
a. gluconeogenesis
b. se glucose↑
c. collagen synthesis ↑
d. GFR↑
e. eosinopenia
A

c

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11
Q
11. Which endocrine disease can cause hypotension?
Select one or more:
a. Sheehan-syndrome
b. Addison-disease
c. Waterhouse–Friderichsen-syndrome
d. Cushing-syndrome
A

a/b/c

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12
Q
12. Synthesized by the zona glomerulosa cells in the adrenal cortex:
Select one:
a. cortisol
b. androgens
c. 11-deoxycortizol
d. dehydroepiandrosterone
e. aldosterone
A

e

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13
Q
  1. Characteristic findings in Cushing-syndrome:
    Select one or more:
    a. random secretion of ACTH
    b. absence of normal diurnal rhythm
    c. TSH-, GH-, LH-, FSH-secretion are increased
    d. Hyperpigmentation
A

a/b

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14
Q
14. The most common cause of chronic primary adrenocortical insufficiency:
Select one:
a. tumor metastasis
b. hemorrhagic necrosis
73

c. tuberculosis
d. fungal infection
e. autoimmune

A

e

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15
Q
  1. True statement for secondary mineralocorticoid-excess:
    Select one:
    a. all of them
    b. se renin level is low
    c. can occur in liver-cirrhosis
    d. can be due to 11β-hydroxylase deficiency
    e. can be due to SIADH
A

c

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16
Q
16. Clinical signs of Cushing-syndrome, except:
Select one:
a. hirsutism
b. dysmenorrhea
c. osteoporosis
d. depression
e. Amenorrhea
A

b

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17
Q
17. Clinical signs of Cushing-syndrome, except:
Select one:
a. depression
b. livid striae
c. amenorrhea
d. virilization
e. central obesity
A

d

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18
Q
18. Cause of secondary mineralocorticoid excess with hypertension, except:
Select one:
a. accelerated hypertension
b. Bartter-syndrome
c. renovascular disease
d. estrogen therapy
e. reninoma
A

b

19
Q
  1. characteristic finding in ectopic ACTH-syndrome:
    select one or more
    a. Hyperkalemia
    b. Hyperpigmentation
    c. Usually the typical symptoms of Cushing syndrome are missing
    d. Random secretion of ACTH
A

b/c/d

20
Q
20. synthesized by the zona fasciculate cells in the adrenal cortex:
elect one
a. Dehydroepiandrossterona
b. Corticosterone
c. Aldosterone
d. Androgens
e. Cortisol
A

e

21
Q
21. signs of acute Addisonian crisis, except:
select one
a. Fever
b. Hypotension and shock
c. Hypoglycemia
d. Edema
A

d

22
Q
22. possible cause of Conn's syndrome, except:
select one or more
a. Adrenocortical hyperplasia
b. 11-alpha-hydroxylase deficiency
c. 21-alpha-hydroxylase deficiency
d. Bartter syndrome
A

c/d

23
Q
23. which of the followings cannot cause secondary adrenocortical insufficiency?
Select one or more
a. Sheehan syndrome
b. Glucocorticoid therapy
c. Addison's disease
d. Waterhouse-Friderchsen syndrome
A

c/d

24
Q
24. 17-ketosteroids in urine are the metabolite of:
Select one:
a. androgens
b. estrogens
c. mineralocorticoids
d. none of them
e. glucocorticoid
A

a

25
Q
25. clinical signs of acute adrenocortical insufficiency, except:
select one
a. Dehydration
b. Hypoglycemia
c. Hypotension
d. Hypernatremia
e. Nausea
A

d

26
Q
26. Signs of primary adrenocortical insufficiency:
Select one or more:
a. hypertension
b. GI disturbances
c. vitiligo
d. weakness, fatigue, losing weight
A

b/d

27
Q
27. Which endocrine disease can cause hypertension?
Select one or more:
a. Cushing-syndrome
b. acromegaly
c. hyperprolactinemia
d. diabetes insipidus
A

a/b

28
Q
28. Causes of secondary hyperaldosteronism:
Select one or more:
a. cardiac decompensation
b. liver cirrhosis
c. nephrotic syndrome
d. diuretic therapy
A

a/b

29
Q
29. Typical signs of 11-b-hydroxylase deficiency:
Select one or more
a. Hypokalemia
b. Hypertonia
c. Hirsutism
d. Early adrenarche
A

a/b/c/d

30
Q
30. Clinical signs of the secondary adrenocortical insufficiency, except;
select one
a. Anemia
b. Lymphocytosis
c. Dehydration
d. Eosinophilia
e. Low ACTH
A

c

31
Q
31. Clinical signs of chronic adrenocortical insufficiency, except;
Select one
a. Hyperglycemia
b. Weight loss
c. Hyponatremia
76
Pathophysiology 1 MCQs - Team effort
d. Abdominal pain
e. orthostatic hypotension
A

a

32
Q
32. hypertension can develop due to
select one or more
a. conn-syndrome
b. 11-b-hydroxylase deficiency
c. sheehan-syndrome
d. hyperthyroidism
A

a/b/d

33
Q
33. Synthesized by the zona fasciculata cells in the adrenal cortex
select one
a. dehydroepiandrosterone
b. cortisol
c. androgens
d. corticosterone
e. aldosterone
A

b

34
Q
34. Clinical signs of chronic primary adrenocortical insufficiency, except:
Select one:
a. GI disturbances
b. hyperpigmentation
c. muscle weakness
d. hypotension
e. hypernatremia
A

e

35
Q
35. Possible causes of secondary hyperaldosteronism:
Select one or more:
a. Bartter-syndrome
b. cirrhosis
c. renovascular disease
d. estrogen therapy
A

a/b/c/d

36
Q
36. Which of the test can be used to diagnose pheochromocytoma?
select one or more
a) Chromatogranin A
b) Se metanephrine, normetanephrine
c) Clonidine suppression test
d) 1311-MIBG scan
A

a/b/c/d

37
Q
  1. Hyperaldosteronism may develop due to
    77

a) Tuberculosis
b) Cirrhosis
c) Bartter-syndrome
d) Estrogen therapy

A

b/c/d

38
Q
37. Possible cause of Conn’s syndrome, except
select one
a) Bartter-syndrome
b) 21a-hydroxylase-deficiency
c) Adrenocortical hyperplasia
d) 17a-hydroxylase-deficiency
A

a/c

39
Q
40. Synthesized by the zona reticularis cells in the adrenal cortex:
Select one:
a. cortisol
b. 11-deoxycortizol
c. corticosterone
d. dehydroepiandrosterone
e. aldosterone
A

d

40
Q
  1. Characteristic findings in ectopic ACTH-syndrome:
    Select one or more:
    a. hyperpigmentation
    b. usually the typical symptoms of Cushing syndrome are missing
    c. hyperkalemia
    d. random secretion of ACTH
A

a/b/d

41
Q
42. 17-OH-corticosteroids are the metabolite of:
Select one:
a. mineralocorticoids
b. none of them
c. androgens
d. Glucocorticoids
e. estrogens
A

d

42
Q
  1. True statements for pheochromocytoma:
    Select one or more:
    a. warm, red limbs
    b. hypertension develops in paroxysm
    c. weight gain
    d. orthostatic hypotension can be observed between attacks
A

b/d

43
Q
44. Possible causes of Conn's syndrome:
Select one or more:
a. 17α-hydroxylase-deficiency
b. adrenocortical hyperplasia
c. Bartter-syndrome
d. 21α-hydroxylase-deficiency
A

a/b

44
Q
45. Signs of primary hyperaldosteronism:
Select one or more:
a. hypokalemia
b. edema
c. polyuria
d. acidosis
A

a/c