thrombosis Flashcards
what type of thrombosis is this?
in a high pressure system
atherosclerotic
platelet rich thrombus
arterial
how do you treat an arterial thrombosis
antiplatelets - aspirin
what type of thrombosis is this
low pressure system
no activation of platelets
activation of coagulation cascade
rich fibrin clot
venous
how do you treat a venous thrombus
warfarin/heparin
what is vrichows triad
stasis
vessel wall
hypercoagubility
what is thrombophilia?
familial or acquired disorder of haemostatic mechanism which are likely to predispose to thrombosis
name some herediatry types of thrombophilia
factor V leiden prothrombin 20210 mutation antithrombin def protein C def protein S def
name a type of acquired thrombophilia
anti-phospholipid syndrome
recurrent thromboses (venous and arterial )
recurrent fetal loss
mild thrombocytopenia
anti-phospholipid syndrome
treat with aspirin and warfarin
a mutation in factor V leiden means resistance to the actions of what?
protein C
