chemo Flashcards
1
Q
what does it mean if the chemo is cell cycle specific?
A
tumour specific (relatively) duration more important than dose
e.g methotrexate
taxol
2
Q
what does it mean if chemo is not cell cycle specific?
A
non tumour specific so kills other cells
dose more important than duration
e,g platinum derivatives
3
Q
what are the general immediate side effects of chemo?
A
bone marrow suppression
gut mucosal damage
hair loss
tired
4
Q
why does chemo fail
A
drug resistance mechanisms
slow tumour doubling time
5
Q
name a fatal complication of chemo ( esp in young patients)
A
neutropenic sepsis
