Pancytopenia Flashcards

1
Q

what is pancytopenia?

A

deficiency of blood cells ( of all lineages but generally excluding lymphocytes)

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2
Q

name a cause of inherited bone marrow failure?

A

Fanconi’s anaemia

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3
Q

names causes of primary bone marrow failure?

A

aplastic anaemia

myelodysplastic syndromes

acute leukaemia

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4
Q

name causes of secondary bone marrow failure?

A

drugs- chemo, alcohol, chloramphenicol

B12/folate deficiency
infiltrive disease
viral
met cancer

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5
Q

what can cause pancytopenia due to decreased production of cells

A

bone marrow failure

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6
Q

what can cause pancytopenia due to increased destruction of cells

A

hypersplenism

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7
Q

aplastic anaemia cellular bone marrow effect

A

hypocellular

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8
Q

myelodysplastic syndroms cellular bone marrow effect

A

hypercellular

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9
Q

B12/folate deficiency cellular bone marrow effect

A

hypercellular

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10
Q

hypersplenism cellular bone marrow effect

A

hypercellular

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