Pancytopenia Flashcards
what is pancytopenia?
deficiency of blood cells ( of all lineages but generally excluding lymphocytes)
name a cause of inherited bone marrow failure?
Fanconi’s anaemia
names causes of primary bone marrow failure?
aplastic anaemia
myelodysplastic syndromes
acute leukaemia
name causes of secondary bone marrow failure?
drugs- chemo, alcohol, chloramphenicol
B12/folate deficiency
infiltrive disease
viral
met cancer
what can cause pancytopenia due to decreased production of cells
bone marrow failure
what can cause pancytopenia due to increased destruction of cells
hypersplenism
aplastic anaemia cellular bone marrow effect
hypocellular
myelodysplastic syndroms cellular bone marrow effect
hypercellular
B12/folate deficiency cellular bone marrow effect
hypercellular
hypersplenism cellular bone marrow effect
hypercellular