Haemopoeisis Flashcards

1
Q

what is haemopoeisis?

A

the formation of blood cells

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2
Q

where are the blood cells all derived from?

A

haemopoietic stem cells which are present in the cellular component of bone marrow ( derived from mesoderm)

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3
Q

what are the 3 main types of blood cell

A

red blood cell
white blood cells
platelets

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4
Q

main function of red blood cell

A

carry O2

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5
Q

main function of white blood cell

A

fight infection

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6
Q

main function of platelets

A

prevent bleeding

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7
Q

where does haemopoiesis occur in the embryo

A

yolk sac

then liver

then spleen

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8
Q

where does haemopoiesis occur at birth?

A

mostly bone marrow ( liver and spleen when needed)

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9
Q

where does haemopoiesis occur from birth to maturity?

A

mainly bone marrow but amount of active places starts to decrease

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10
Q

where does haemopoiesis occur in adults?

A
bone marrow of:
skull
ribs
sternun
pelvis
prox femur
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11
Q

life of red blood cell

A

120 days

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12
Q

life of neutrophil

A

7-8 hours

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13
Q

life of platelet

A

7-10 days

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14
Q

immediate red cell precursor?

A

reticulocyte

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15
Q

what regulates neutrophil maturation?

A

GCSF

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16
Q

how would you assess haemopoeisis?

A

blood count
blood film
cell indices
bone marrow

immunophenotyping- study of antigen expression