the lymphoid system Flashcards
name the primary lymphoid tissue
bone marrow and thymus
where does T cell maturation take place
thymus
where does B cell maturation take place
bone marrow
name the secondary lymphoid tissue
lymph nodes
spleen
tonsils
bone marrow
what are lymph nodes
small oval bodies up to 2.5 cm located on course of lymphatic vessels ( passive movement of lymph with valves)
where is lymph filtered
in the parenchyma in the lymph node and then it gets returned to blood
what organ filters the blood
spleen
name some features of splenomegaly
dragging in LUQ
pain if infarction
discomfort with eating
hypersplenism
what would cause a predominant B cell response?
infection
autoimmune
what would cause a predominant T cell response>
viral infection
what would cause a strong phagocytic response
draining a tumour site
name some causes of splenomegaly
infection- EBV, TB, malaria, thypoid
amyloid
Guachers
congestion- congetsive heart failure, portal hypertension, liver cirrhoso
haem-lymphomam leuakemia
RA
SLE
what can cause hyposplensim
splenectomy
also coeolic, sarcoidosis, sickle cell
