anticoagulant drugs and antiplatelets Flashcards
indications for anticoagulant drugs
venous thrombosis
atrial fibrillation
what drug potentiated antithrombin
heparin
what are the 2 forms of heparin
unfractionated
low molecular weight
how do you monitor low molecular weight heparin
anti- xa assay
how do you monitor unfractionated heparin
APTT
how can heparin be give
IV or SC
what are the complications of heparin
bleeding
osteoporosis with long term use
heparin induced thrombocytopenia
how does warfarin work
vitamin K antagonist
where is vit K absorbed
upper intestine
what do you need to absorb vitamin K
bile salts
what are the vit K dependent factors
II
VII
IX
X
when should warfarin be taken
same time everyday
6pm is recommended
how does dabigatran work
thrombin inhibitor
how does rivaroxaban work?
Xa inhibitors
how does aspirin work?
inhibits cyclo-oxygenase
