Throat symptom/complaint Flashcards
Predisposing factos for Candida pharyngitis
HIV infection Diabetes mellitus Broad spectrum antibiotics Corticosteroids, including inhalers Dentures Debility
Symptoms and signs of Candida phyaryngitis
Presentation - Milky white growths on palate, buccal, gingival mucosa, pharynx and dorm of the tongue.
If scraped away a bleeding ulcerated surface remains
Metallic taste
Sore throat and tongue
dysphagia
Mx of Candida pharyngitis
Determine underlying cause
Nystatin suspension rinse and swallow QID
or amphotericin 10mg lozenge dissolved slowly in oral cavity, 6hrly for 7-14days.
Presentation of Hand, foot and mouth
fever sore throat dysphagia oral tiny papulovesicles erythematous halo
Cause of Hand, foot and mouth
Coxsackie virus A
Transmission and incubation of hand, foot and mouth
Face - oral and incubation for 2-6 days
Cause of Glandular fever
Epstein Barr Virus (Infectious monocytosis)
Transmission of Epstein Barr Virus
Youth, close contact, saliva, kiss
Incubation time for EBV
1-2 months
Pathogenesis of EBV
EBV infect epithelium cells of the URT and infect B lymphocytes where they start multipling in the B lymphocytes. From there they spread and infect other organs by infected B lymphocytes.
EBV specific CD8+ T cells - defines (atypical lymph)
Symptoms of EBV
15-25 yrs with a painful throat that take 7d to reach the peak. Prodromal fever, malaise, lethargy Anorexia, myalgia Nasal quality voice Skin Rash
Signs of EBV infection
URTI+ Petechiae on palate Enlarged tonsils with or without Periorbital oedema Lymphadenopathy Splenomegaly - enlarged spleen = easy rupture - youth death Hepatitis The rash - Primary rash 5%, Secondary rash when treatment with ampicillin, amoxycillin and some with penicillin
Cx of EBV infection
Hepatitis
Spleen rupture - they can die from minor trauma
Organ failure - fatal
Dx of EBV infection
FBC - Absolute lymphocytosis
Blood firm - atypical lymphocytes
heterophil antibodies or Monospot test or EBV IgM test
Tx of EBV infection
Prognosis - self limited 4-6 wks
Symptomatic support - paracetamol
Parenteral corticosteroids only in most severe cases
Hydration - admit if unable to tolerate fluids
Symptoms of Diptheria
Insidious onset Fever SOB Sore throat Dysphagia Cough Nausea and vomiting
Signs of Diptheria
Pharynx inflamed and swollen with enlarged tonsils Pseudomembrane Hoarse voice Lymphadenopathy Cutaneous diphtheria (non healing ulcer)
Cx of Diptheria
Aspiration of pseudomembrane and airway obstruction
spread of exotoxin to cause myocarditis and HF
Peripheral neuritis
Tx of Diptheria
Throat swabs
Antitoxin
Penicillin or erythromycin 500mg QID for 10 days
Isolate patient
Cause of diptheria
Corynebacterium diphtheria which is gram +ve, pleomorphic bacilli, with exotoxin AB
Prevention of diptheria
DPT at 2m, 4m, 6m, 4yr, 10yr, 15yr and booster every 10yrs
Pathogenesis of diptheria
Infection results in mucosal necrosis with fibrinopurulent exudate (pseudomembrane).
Most common causes of Rhinitis
Rhinovirus most common cause >100 serotypes Other causes Influenza Parainfluenza Corona (SARS) Adenovrius RSV May be bacteria after 7-10 days Allergy - frequent or persistent symptoms
Rhinovirus
Transmission
Incubation period
and epidemiology
Seasonal Highly contagious Transmission Droplet spread by sneezing, coughing, hand contact with the nose, eyes or face. Incubation period 2-4 days Prevention hand hygiene