Thorax: Embrology, Non-Cardiac Flashcards

1. recall the formation of the intraembryonic coelom from lateral and longitudinal folding of the embryo 2. describe the effect of embryonic folding on the placement of the developing heart and septum transversum 3. describe the division of the intraembryonic coelom into the pericardial, pleural, and peritoneal cavities 4. describe the formation of the diaphragm 5. describe the contributions of endoderm and mesoderm to the adult structures of the lung 6. explain some common congen

1
Q

costodiaphragmatic recess

A
  1. arises- from paraxial mesoderm> somites> myotomes> muscles of anterolateral trunk
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2
Q

innervation, diaphragm (explain embryologically)

A
  1. central: C3-5, location of central ligament

2. costal rim: innervated by lower intercostal nerves (origin is from the lateral body wall)

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3
Q

Diaphragm: what is the embryonic primordium that gives rise to the adult central tendon?

A

septum transversum

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4
Q

Diaphragm: what is the embryonic primordium that gives rise to the adult muscular crura?

A

dorsal mesentry of esophagus

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5
Q

Diaphragm: what is the embryonic primordium that gives rise to the adult outer rim of diaphragm?

A

body wall

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6
Q

Diaphragm: what is the embryonic primordium that gives rise to the adult diaphragmatic musculature?

A

cervical somites

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7
Q

Diaphragm: what is the embryonic primordium that gives rise to only a small portion of the diaphragm?

A

pleuroperitoneal membrane

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8
Q

what structure separates the foregut and respiratory diverticulum during week 4?

A

the tracheoesophagel ridge< foregut< endoderm

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9
Q

what is the tracheoesophagel ridge?

A

a structure that separates the foregut and respiratory diverticulum during week 4

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10
Q

visceral pleura & stroma of trachea, bronchi, & lungs (smooth muscle, blood vessels, cartilage)

A

lateral plate mesoderm, visceral layer

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11
Q

cervical somites C3-C5

A

give rise to most of the central diaphragmatic musculature

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12
Q

fate map: intraembryonic coelom

A

vesciles lateral plate> intraembryonic coelom> pericardial cavity + peridicardoperitoneal canals

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13
Q

what two structures fuse to separate the thorax from the abdomen?

A

pleuroperitoneal membrane and septum transversum

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14
Q

fate map: parenchyma of lungs

A

endoderm> foregut> lung buds> parenchyma of lungs

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15
Q

pleuropericardial membranes

A

parietal layer of lateral plate mesoderm>
peuropericardial membrane>
fibrous pericardium

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16
Q

What are the major events of thorax development?

A
  1. fusion of lateral plate vesicles: forms intraembryonic coelom
  2. longitudinal and lateral folding: forms the
17
Q

Curve of the U (Day 20, intraembryonic coelom)

A

pericardial space

18
Q

Limbs of the U (Day 20, intraembryonic coelom)

A

pleural and peritoneal cavities

19
Q

primitive body cavity

A

intraembryonic coelom

20
Q

what event separates the primitive body cavity from the amniotic cavity?

A

lateral folding

21
Q

septum transversum

A
  1. arises from: lateral plate, parietal layer
  2. relations: initially cranial to primitive heart, ends caudal to primitive heart
  3. Significance:
    a. forms central tendon of diaphragm
    b. helps separate the thorax/ abdomen
22
Q

the intraembryonic coelom gives rise to which 3 body cavities

A
  1. one percicardial cavity
  2. two pericardioperitoneal canals
  3. one peritoneal cavity

partitions: septum transversum, pleuroperitoneal membrane, pleuropericardial membrane