Thermodynamics Flashcards

1
Q

What is the first law of thermodynamics?

A

Energy can neither be converted nor destroyed

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2
Q

What is the second law of thermodynamics?

A

All energy transformations ultimately lead to more disorder, an increase in entropy

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3
Q

What is enthalpy defined as?

A

The total energy within a system

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4
Q

What is entropy defined as?

A

The disorder within a system

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5
Q

What is the equation to calculate gibbs free energy?

A

TriangleG=triangleH - T triangle S

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6
Q

What is free energy measured in?

A

Kcal/mol

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7
Q

What does a delta G less than 0 indicate?

A

The reaction is spontaneous and energy releasing

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8
Q

What does delta G greater than 0 indicate?

A

That the reaction is spontaeous backwards (endergonic)

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9
Q

What does a delta G equal to 0 mean?

A

The reaction is at equilibrium

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10
Q

What type of delta G do biological reactions require?

A

Positive delta G, since they require more order rather than less

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11
Q

What is meant by energy coupling?

A

An energetically unfavourable reaction is driven by an energetically favourable reaction.

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12
Q

Define metabolism

A

Metabolic processes are chemical reactions and these often involve generation of heat.

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13
Q

Define metabolic pathways

A

A series of connected chemical reactions that feed one another.

The pathway takes in one or more starting molecules and, through intermediates, converts them into products.

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14
Q

Define catabolism

A

The breakdown of complex molecules in living organisms to form simpler ones, together with the release of energy; destructive metabolism.

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15
Q

Define anabolism

A

Simpler substances are combined to form more complex molecules
Require energy

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16
Q

How do exergonic reactions save free energy?

A

By forming ATP

17
Q

What is the definition of an apoenzyme?

A

Require non-protein co-factors

18
Q

What makes up a holoenzyme?

A

Apoenzyme and its cofactors

19
Q

Describe the structure of ATP

A

A nucleoside triphosphate, consisting of:
Nitrogenous base (adenine)
Ribose sugar
Three serially bonded phosphate groups

20
Q

Structure of ADP

A

A sugar backbone attached to adenine and two phosphate groups bonded to the 5 carbon atom of ribose.

21
Q

What is NAPD+?

A

Coenzyme

Acts as universal electron carrier, accepting electrons and hydrogen atoms to form NADPH

22
Q

NAD

A

Influence many key cellular functions:
metabolic pathways, DNA repair, chromatin remodelling, cellular senescence and immune cell function.

Critical for maintaining tissue and metabolic homeostasis and for healthy ageing.

23
Q

How does ATP contribute to metabolic flow?

A

ATP captures chemical energy from the breakdown of food molecules & uses it to fuel other cellular processes.

24
Q

What is ADP essential in?

A

Photosynthesis and glycolysis.

25
Q

What is ADP the end product of?

A

ATP losing one of its phosphate groups

26
Q

How is ADP converted to ATP?

A

ADP reconverts to ATP by the addition of a phosphate group to ADP.

27
Q

When is NADP+ created?

A

Anabolic reactions