therapeutic evidence Flashcards
Principles to determine quality use of medicines
Clinical Efficacy and Safety - is it clinically effective
Patient factors - e.g. age or ethnicity
Pregnancy or breastfeeding
Other medical conditions
what are Case Controlled studies
Case Controlled studies compare two groups of people: those with the disease or condition under study (cases) and a very similar group of people who do not have the disease or condition (controls).
how do Randomised controlled trials work?
RCT) are prospective studies that measure the effectiveness of a new intervention or treatment.
RCTs are the gold-standard for studying causal relationships as randomisation eliminates much of the bias inherent with other study designs.
WHAT IS EACH:
Absolute risk measure
Absolute risk reduction
Number needed to treat
Relative risk
Relative risk Reduction
Absolute risk measure
Absolute risk reduction
Number needed to treat
Relative risk
Relative risk Reduction
RESOURCES
where is drug product informaiton found?
The product information is a regulatory document produced at the time of market approval.
Each product also has a consumer medicines information or CMI) leaflet.
These can be found on the TGA website or available online in MiMs.
what resource would you use to find out about regulatory status ( indications , side effects and some common off licence uses & good clinical summaries and comparative info.
info about drug interactions.
There is information about adverse effects often put into context for the clinical setting
AMH
what are thePrinciples to determine quality use of medicines
