cardiovasular system + other drugs and cardio info

Question 1

Angiotensin-converting enzyme inhibitors are typically named with what suffix?

Answer 1

The suffix -pril; such as captopril

Question 2

Cardiac glycosides are typically named with what suffix?

Answer 2

The suffix -oxin; such as digoxin

Question 3

β-Antagonists are typically named with what suffix?

Answer 3

The suffix -olol; such as propranolol

Question 4

Drugs that end in -olol are generally what class of drug?

Answer 4

β-Antagonists

Question 5

Drugs that end in -pril are generally what class of drug?

Answer 5

ACEi

Question 6

renin-angiotensin-aldosterone system

Answer 6

renin-angiotensin-aldosterone system
a drop in BP alters Na+ and water retention
- sympathetic nervous system stimulates increase in renin release and vasopressin, increase angiotensin I, increase angiotensin II, aldosterone produced, increased H2O and Na+ retention, increase CO
.

Question 7

Mwhat class is digoxin and what is the MOA

Answer 7

digoxin is derived from foxglovem and is used for arterial flutter,heart failure.

it works by slowing the HR down and improve the filling of your ventricles (two of the chambers of the heart) with blood. For people with atrial fibrillation, where the heart beats irregularly, a different volume of blood is pumped out each time

Question 8

5HT3 (serotonin) antagonists (-setron)
and examples

Answer 8

Examples:
- Granisetron
- Odansetron
- Palonosetron
- Tropisetron
Mechanism of action:
- Bind to and block central and peripheral 5HT3 receptors
Adverse effects:
- Generally well tolerated, but can cause headaches and constipation
- Palonosetron is better at preventing post-operative vomiting than odansetron

Question 9

Dopamine antagonists
and example of the name and what they do

Answer 9

1. Metoclopramide
   Adverse effects:
   - Dizziness
   - Akathisia
   - Drowsiness
   - Headache
   Contraindications:
   - Parkinson’s
   - Depression
   - People under 20
2. Prochlorperazine
   Adverse effects:
   - Drowsiness
   - Akithisia
   - Parkinsonism
   - Constipation
   - Dry mouth
   Contraindications:
   - Parkinsons
   - Depression