The Nephron- Renal corpuscle Flashcards

1
Q

What are the two structural components of the nephron?

A

The renal corpuscle and the renal tubule

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2
Q

What are the three functions of the kidney?

A

Filtration, reabsorption, secretion

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3
Q

There are ____ nephrons located both in the renal ______ and the renal _______

A

1.25 million
cortex
medulla

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4
Q

Describe a cortical nephron

A

85% Nephron tubules only go a short way into the pyramid, the glomerulus goes further

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5
Q

Describe a juxtamedullary nephron

A

15% These tubules are very long, usually extending to the apex of the pyramid

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6
Q

Where are glomeruli?

A

In cortex, are closer to the base of the pyramid

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7
Q

What two parts make the renal corpuscle?

A

The glomerulus and Bowman’s capsule

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8
Q

What does the glomerulus look like?

A

A “tuft” of fenestrated capillaries, like a ball of yarn

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9
Q

In the glomerulus:
An _______ arteriole brings blood in, ______ in diameter
An _______ arteriole drains blood out- _______ in diameter

A

Afferent/ larger

Efferent/smaller

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10
Q

Bowman’s capsule is also called the “…” What’s it’s function?

A

Glomerular capsule
Surrounds the glomerulus to “catch” the filtrate
A collecting area for filtrate being filtered from the glomerulus

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11
Q

What epitheliums make up Bowman’s capsule?

A

Made up of a visceral and parietal epithelium

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12
Q

What makes up the visceral epithelium of Bowman’s capsule? What does it do?

A

podocytes, that cover the capillary

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13
Q

What makes up the parietal epithelium of Bowman’s capsule?

A

Simpel squamous epithelium

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14
Q

Where is the filtration membrane located?

A

In Bowman’s glad

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15
Q

What does the filtration membrane do?

A

This is non-selective filtering, it only filters by size

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16
Q

What are the three parts of the filtration membrane?

A

1- Pores of the fenestrated capillary
2- Basement membrane
3- Filtration slit- A space between interdigitating pedicels

17
Q

What is a pedicel? What does it come off?

A

Pedicels come off the foot processes of podocytes, like interlaced fingers

18
Q

What passes through the filtration membrane?

A

Water, waste, sodium, dissolved solutes, and glucose pass through

19
Q

What doesn’t pass through the filtration membrane?

A

RBCs, WBCs, and loose proteins like albumins and transporters do not pass

20
Q

How much blood is filtered in 40 minutes? In a while day?

A

40 min- Total Blood Volume

1 day- 180L

21
Q

Because the efferent arteriole is narrower in diameter than the afferent arteriole, blood in the glomerular capillaries is under ________ and ______ takes place

A

Pressure

Filtration

22
Q

Liquid and solutes are forced through the _______ ______, _______ _________, and _______ _______, and ends up inside the capsular space.

A

capillary pores
basement membrane
filtration slits