Kidneys: Reabsorbtion Flashcards

1
Q

What are the three processes of the kidney?

A

Filtration
Reabsorption
Secretion

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2
Q

As filtrate passes through the tubules, 99% of it is returned to the______ ______, so back to the blood

A

peritubular capillaries

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3
Q

Both active and ______ processes are at work here

A

passive

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4
Q

___% of total energy requirements for the kidney is Na+ reabsorption, 6% of calories at rest

A

80%

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5
Q

What are some things that are reabsorbed?

A

Na+ K+ Glucose, H20, amino acids

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6
Q

What do we have to do to “move” water? Set a gradient- Surrounding tissues must become _______- need solutes to pull H2O in

A

hypertonic

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7
Q

In which two places does reabsorption take place?

A

Glomerulus

Proximal convoluted tubule

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8
Q

What is reabsorbed at the glomerulus?

A

All plasma solutes except proteins are able to enter the filtrate freely

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9
Q

The solute concentration in the filtrate from the glomerulus is the same as the blood, that is ___-tonic.

A

Isotonic

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10
Q

How is the isotonic gradient at the glomerulus changed so Na+, Cl- and H2O out of the filtrate?

A

Na+ and active transport to do this

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11
Q

What is reabsorbed at the PCT?

A

Water, solutes, Na+, Cl-

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12
Q

What adaptations do the cells of the PCT have to assist reabsorption?

A

All cells lining the PCT have a brush border microvilli on the apical surface, also have many large mitochondria to produce ATP for active transport

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13
Q

___ reabsorption is critical to everything else

A

Na+

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14
Q

At the basal portion of PCT cell there are many Na+/K+ pumps. By moving ___ out of the PCT cell into the ECF, there is a permanent low ___ level in the PCT cell. This causes Na+ to diffuse into the ____ from the filtrate.

A

Na+
Na+
Cell

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15
Q

___ will follow the Na+ into the PCT cell from the filtrate

A

Cl-

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16
Q

In the PCT an osmotic gradient is set between _______ and _______ that H2O will follow to be retained.

A
Tubular fluid (ECF)
Tissue fluid (Capillary)
17
Q

Glucose is co-transported with Na+ using _____ across apical surface and by _____ ______ across basal surface.

A

SGLT

facilitated diffusion