The muscular system Flashcards

1
Q

What are the main properties of muscles?

A

Electrical excitability - ability to respond to stimuli from neurotransmitter
Contractile - can shorten in response to an action potential
Extensible - can stretch
Elastic - will return to original shape after contraction

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2
Q

What is the structure of skeletal muscle?

A

Muscle cell covered by endomysium (delicate connective tissue)
Group of fibres covered by perimysium
Whole muscle covered by epimysium

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3
Q

What are the types of levers?

A

1st class - fulcrum between load and pull
2nd class - load between fulcrum and pull
3rd class - pull between fulcrum and load

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4
Q

Describe the structure of cardiac muscle fibres

A

1 nucleus
large mitochondria
sarcolemma with T-tubules
T-tubules transverse fibres, allowing a route for Ca2+
Myofibrils throughout, but more disorganised with sarcomeres as a contractile element

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5
Q

Describe the structure of smooth muscle fibres

A

Non-striated involuntary muscle
Enables involuntary visceral contraction
No T-Tubules
Loosely organised sarcoplasmic reticulum
Thick and thin filaments pull into a ball when contracted

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6
Q

Describe the sliding filament mechanism

A
  1. Detachment - ATP bind to myosin head, myosin detaches from actin
  2. Hydrolysis - ATP splits into ADP +Pi, causes myosin head to adopt ready position
  3. Cross-bridge - Ca2+ from impulse reveals binding site, myosin head binds to actin
  4. Release - Bound ADP +Pi are released, myosin head performed a power stroke back to relaxed state
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7
Q

What is the latent, contraction and relaxation period?

A

Latent - time between stimulation and contraction (2ms)
Contraction - Crossbridge formation (15ms)
Relaxation - When peak tension is developed and stimuli is removed (25ms)

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8
Q

What are the effects of strength, endurance and prolonged inactivity?

A

Strength - hypertrophy (more myofilaments in each fibre)
Endurance - Increased blood flow to muscles enabling in to maintain moderate activity for longer
Prolonged inactivity - disure atrophy

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