Microstructures of the nervous system Flashcards
What are the main cell types of the PNS?
Schwann cells - form myelin sheath
Satellite cells - provide structural support, regulate exchange of material between neural body and interstitial fluid
What are the main cell types of the CNS?
Astrocytes - contains microfilaments to strengthen neurons
Oligodendrocytes - form + maintain myelin sheath
Microglial- phagocytic properties
Ependymal - produce + assist in circulation of cerebrospinal fluid
How is the resting membrane potential maintained?
Na enters the cell via voltage gated channels
K leaves via voltage gated channels
The Na-K pump sends 3NA+ out for 2K+ in
What are the phases of an action potential?
- Na+ channels open, Na+ enters the cell
- K+ channels open, K+ leaves the cell
- Na+ channels become refractory, no more Na+ can enter
- K+ continues to leave the cell, causing the return of resting potential
- K+ channels close and extra K+ diffuse away
What are the two refractory periods?
Absolute - From when Na+ gates open until just after they close, neuron won’t respond to additional stimuli
Relative - Until K+ gates close and membrane returns to threshold, neuron will respond to additional stimuli if strong enough
What are the two types of summation?
Spatial - input from multiple cells
Temporal - series of synaptic potentials occurring within ms of each other