The Grand Tour of the Alimentary Canal Flashcards
GI tract
series of hollow organs joined in a long, twisting tube from the mouth to the anus
what makes up the GI tract
mouth, oesophagus, stomach, small intestine, large intestine, and anus
accessory organs
salivary glands, liver, pancreas, gallbladder
main functions of digestive system
digestion, secretion, absorption, motility
digestion
breaking down of the food we eat into simple substances that our bodies can absorb
Digestive absorption
passage of the end products of digestion from the gastrointestinal tract into the blood, and lymphatic vessels.
secretion
process by which substances are produced and discharged from a cell, gland, or organ for a particular function in the organism or for excretion.
motility
ability of an organism to move independently, using metabolic energy.
What is the function of the mouth?
Break down foodstuff by chewing, saliva acting as a lubricant
What is the function of the oesophagus?
Conduit between the mouth and stomach
What is the function of the stomach?
Digestion of proteins
Foodstuff reduced to liquid form
Storage
Sterilisation
What is the function of the pancreas?
Digestive enzymes for digestion of fats, carbohydrates and proteins
What is the function of the liver?
Produce bile salts for digestion/absorption of fats in the small intestine
What is the function of the gallbladder?
Stores and concentrates bile
What is the function of the small intestine?
Final stages of chemical digestion and nutrient absorption
What is the function of the large intestine?
Water absorption
Bacterial fermentation and formation of faeces
In basic terms what is the alimentary canal?
Continuous hollow tube from the oesophagus to the rectum
How long is the alimentary canal?
About 8m long
What can be said about the structural formation of the alimentary canal throughout its length?
it is the same throughout its length with 4 distinct layers
What are the 4 distinct layers of the alimentary canal?
Mucosa
Submucosa
Muscularis external
Serosa/adventitia
Where is stratified squamous epithelium found?
Mouth
Oesophagus
Anal canal
Where is simple columnar epithelium?
Stomach
Small intestine
Large intestine
What is the functions of epithelium?
Separate lumen of alimentary canal from the body
Synthesis and secretion of digestive enzymes, hormones and mucus
Absorbs products of digestion
What are the layers of the mucosa?
mucous epithelium
Lamina propria
Muscularis mucosae
What is lamina propria?
Loose connective tissue (glands, blood and lymph vessels)
What is muscularis mucosae?
Thin smooth muscle layer
What is submucosa?
Thick, irregular connective tissue to support mucosa
What does the submucosa contain?
neurons
Blood vessels
Lymphatic vessels
What do neurons form in the submucosa?
Submucosal plexus (parasympathetic)
Is the submucosal plexus sympathetic or parasympathetic?
parasympathetic
Where are submucosal glands found?
Oesophagus
Duodenum
What makes up the muscularis externa?
Two concentric thick layers of smooth muscles (inner layer and outer layer)
What is the inner layer of the muscularis externa?
Circular muscle
What is the outer layer of the muscularis externa?
Longitudinal muscle
What is the function of the circular muscle?
Constrict lumen
What is the function of the longitudinal muscle?
Shortens tube
What is the function of the muscularis externa?
Produce motility for peristalsis and segmentation
What is found between the circular and longitudinal muscle?
Myenteric plexus
What is the enteric nervous system (ENS) formed from?
Submucosal and myenteric plexuses
What does the enteric nervous system (ENS) allow?
Independent control of gut function
What is the purpose of the adventitia outside of the peritoneum cavity?
Attaches oesophagus and rectum to surrounding structures
What is the difference between serosa and adventitia?
Serosa covers organs that freely move inside of a cavity
Adventitia bounds organs to supporting structures
What kind of tissue is the serosa/adventitia?
Connective tissue
What does serosa surround inside the peritoneal canal?
Stomach
Small intestine
Large intestine
What provides autonomic control of alimentary function?
Long (parasympathetic) and short (ENS) reflexes
What provides parasympathetic innervation to alimentary function?
Vagus nerve (except salivation which is controlled by facial [VII] and glossopharyngael [IX] nerve
What nerves control salivation?
Facial (VII) cranial nerve
Glossopharyngeal (IX) cranial nerve
What effect does the parasympathetic nervous system have on alimentary function?
Increases secretion and motility
What provides sympathetic innvervation to alimentary function?
Thoracic splanchnic nerves
What effect does sympathetic innervation have on the alimentary function?
Decreases secretion and motility (except salivation)
What 3 main arteries supply the GI tract?
Celiac trunk
Superior mesenteric artery
Inferior mesenteric artery
What do the celiac trunk, superior mesenteric and inferior mesenteric branch from?
abdminal aorta
What does the celiac trunk artery supply?
Stomach
Small intestine
Pancreas
Liver
What does the superior mesenteric artery supply?
Small intestine
Caecum
Ascending colon
Transverse colon
What does the inferior mesenteric artery supply?
Descending colon
Sigmoid colon
Rectum
What veins drain the stomach?
Gastric veins
What veins drain pancreas?
Splenic vein
What does the superior mesenteric vein drain?
Small intestine
Caecum
Ascending colon
Transverse colon
What does inferior mesenteric vein drain?
Decending colon
Sigmoid colon
Rectum
what veins drain into the hepatic portal vein?
Gastric veins
Splenic vein
Superior mesenteric vein
Inferior mesenteric vein
What is the venous drainage from the hepatic portal vein?
Hepatic portal vein -> hepatic vein -> inferior vena cava
simple epithelial
one cell layer
stratified epithelium
many layers
stratified squamous
Mouth, oesophagus, anal canal
simple columnar
Stomach, small & large intestine
Connective tissue outer layer of alimentary canal
Outside peritoneal cavity:
Adventitia attaches oesophagus and rectum to surrounding structures
Connective tissue outer layer of alimentary canal
Inside peritoneal cavity:
Serosa surrounds stomach, small intestine and large intestine
Muscularis Externa
Two concentric thick layers of smooth muscle
inner layer of muscularis externa
circular muscle (constricts lumen)
outer layer of muscularis externa
longitudinal muscle (shortens tube)
what type of motility is produced by muscularis externa
peristalsis, segmentation
where is Myenteric (Auerbach’s) plexus found
between circular and longitudinal muscle
Submucosal + myenteric plexuses =
enteric nervous system (ENS) ⇒ independent control of gut function
Autonomic control:
Long (parasympathetic) and short (ENS) reflexes
(both afferent and efferent)
Parasympathetic
vagus nerve (X)
parasympathetic exception
salivation ⇒ facial (VII) and glossopharyngeal (IX)
Stimulatory
⇑ secretion
⇑ motility
Sympathetic
⇒ splanchnic nerve
Inhibitory (except salivation)
⇓ secretion
⇓ motility
Celiac trunk
Stomach
Small intestine
Pancreas
Liver
Superior mesenteric
artery
Small intestine
Caecum
Ascending colon
Transverse colon
Inferior mesenteric
artery
Descending colon
Sigmoid colon
Rectum
Stomach
Gastric
veins
Pancreas
Splenic
vein
Small intestine
Caecum
Ascending colon
Transverse colon
Superior
mesenteric
vein
Descending colon
Sigmoid colon
Rectum
Inferior
mesenteric
vein
gastric veins, splenic vein, superior mesenteric vein, inferior mesenteric vein
hepatic portal vein
hepatic portal vein
hepatic vein
hepatic vein
IVC