The Gallbladder: 9-06-13 (BIO181) Flashcards
- pear shaped muscular sac
- located in indentation of liver’s right lobe
- stores and concentrates bile prior to excretion into the small intestine
- releases bile into the duodenum
the gallbladder
regions of the gallbladder
fundus
body
neck
extends from gallbladder until it joins with the common hepatic duct and forms the common bile duct
cystic duct
full gallbladder contains ___-___ mL of bile
40-70
- the composition of bile is gradually changed in the gallbladder
- water is absorbed
- bile salts and solutes become concentrated
bile modification
regulatory mechanisms center around ___ where acids are neutralized and enzymes added
duodenum
___ and ___ mechanisms coordinate activities of digestive glands
neural; hormonal
- motor neurons synapse onto the digestive tract and release neurotransmitters
- prepare digestive tract for activity
- inhibit gastrointestinal activity
- coordinate movement of materials along the digestive tract
neural mechanisms
-intestinal tract secrets peptide __ that work at several regions of digestive tract and in the accessory glandular organs
hormones
___ ____ cells produce several hormones that work to coordinate digestive functions
duodenal enteroendocrine
- is released when chyme enters the duodenum
- increases secretion of bile and buffers by the liver ans pancreas
secretin
- secreted in duodenum when chyme contains lipids and partially digested proteins
- accelerates pancreatic production and secretion of digestive enzymes
- relaxes hepatopancreatic sphincter and gallbladder to eject bile and pancreatic juice into duodenum
Cholecystokinin (CCK)
- is secreted when fats and carbohydrates enter small intestine
- slows things down
Gastric inhibitory peptide (GIP)
- stimulates secretion of intestinal glands
- dilates regional capillaries
- inhibits acid production in stomach
vasoactive intestinal peptide (VIP)
- secreted by g cells in duodenum when incompletely digested proteins are exposed
- promotes stomach mobility
- stimulates the production of acids and enzymes
gastrin
- released when chyme enters the small intestine
- stimulates mucin production by submucosal glands of duodenum
enterocrinin
it takes about _ ____ for materials to pass from the duodenum to end of ileum
5 hours
- Movements of the ___ increases absorptive effectiveness
- stir and mix intestinal contents
- constantly change environment around epithelial cells
mucosa
- horseshoe shaped
- extends from end of ileum to anus
- lies inferior to stomach and liver
- frames the small intestine
the large intestine
- pouch like first portion of the large intestine
- receives material arriving from the ileum
- stores material and begins compaction
cecum
- a slender, hollow appendage that is attached to the cecum
- dominated by lymphoid nodules
- immune response
appendix
- has a larger diameter and thinner wall than small intestine
- walls form series of pouches (haustra) that permit expansion and elongation
colon
- forms the last 15cm (6in) of digestive tract
- expandable organ for temporary storage of feces
- movement of fecal material into it triggers urge to defecate
rectum
- the ___ ____ is the last portion of the rectum
- contains small logitudinal folds called anal columns
anal canal
- also called the anal orifice
- exit of anal canal
anus
- circular muscle layer of muscularis externa
- has smooth muscle cells that are INVOLUNTARY
internal anal sphincter
- encircles distal portion of anal canal
- a ring of skeletal muscle fibers that are VOLUNTARY
external anal sphincter
-less than __% of nutrient absorption occurs in the large intestine
10
bile salts are reabsorbed in the ___ and then transported back to the liver for secretion into bile
cecum
- required by liver for synthesizing clotting factors
- fat soluble
vitamin K
- important in glucose metabolism (for energy)
- water soluble
biotin
- required in manufacture of steroid hormones and some neurotransmitters
- water soluble
B5
-reabsorption of water
-compaction of intestinal contents into feces
-storage of fecal material prior to deification
all happen in the __ ___.
large intestine
-bacteria in the ___ ___ convert biliruben to substances that can ultimately be excreted
large intestine
bacteria break down ___ in feces and generate ammonia, nitrogen compounds, and hydrogen sulfide
peptides
bacteria feed on indigestible ____ to produce intestinal gas
carbohydrates