CH 15-18 Packets (BIO 181) Flashcards
what are the two properties of sound and how are they measured?
loudness: amplitude dB
pitch: frequency Hz
where does the external ear end?
tympanic membrane
where do we see the first and second level of amplfication of sound
1st: ossicles
2nd: oval window
where does transduction of sound energy occur?
cochlea
what are the three fluid filled compartments of the cochlea
scala vestibuli
scala media
scala tympani
in which compartments are perilymph and endolymph found?
perilymph: scala vestibuli; scala tympani
endolymph: scala media
what are the receptor cells
hair cells
what types of ion channels are located at the tips of the stereocillia of hair cells
mechanically gated
what happens when the steriocillia bend towards the tall stereocillia
channels open (depolarization) potassium enters cell
what happens when the steriocillia bend towards the short steriocillia
channels close (hyperpolarization) potassium doesnt enter cell
describes the neural pathway for sound
hair cells synapse on afferent axons of CN VIII, cochlear enters brainstem, synapse with 2nd order neuron to 3rd order neuron and travels to auditory cortex to cranial nerve 8
what are the two branches of the vestibylocochlear nerve and what is their function
- vestiular—-> equilibrium
2. cochlear—> hearing
what are the three types of cells in the olfactory epithelium and what is their function
- supporting cell—> secrete mucous
- receptor cells—>neurons that respond to odorants
- basal cells—> regeneration
what important proteins are found in mucus and what is their function
olfactory binding protiens
Describe the steps involved in olfactory signal transduction
chemicals dissolve in mucus, travel to receptor cells, trigger production of cAMP—> depolarization of receptor cells, then receptors send axons through cribiform plate to brain
what happens to the axons of the receptor cells of olfaction once they have depolarized
receptors send their axons through cribriform plate towards brain
map out the neural pathway for olfaction
olfactory nerve—> olfactory bulb—>olfactory tract to olfactory cortex (NO THALAMUS)
what are the three types of lingual papillae
curcumvallate, fungiform, filiform
how many taste buds would be found in the circumvallate papillae
100
how many tast buds would be found in the fungiform papillae
5
what is the only function of th filiform papillae
only to provide friction (NO TASTE BUDS)
what two types of cells are found in the taste buds
basal and gustatory
describe the four primary tastes and what rimary transduction mechanism is used by each
- sour: H+ binding with K+ (depolarize)
- salty: Na+(depolarize)
- bitter: nitrogen (ligands) (depolarize)
- sweet: ligands (depolarize)
describe the neural pathway for taste
receptor cells to afferent neurons via CN VII, IX, X –> CNs synapse to 2nd order neurons that project to thalamus, 3rd order neurons terminate in gustatory cortex in parietal lobe.
what does the somatic nervous system control?
voluntary control of skeletal muscles
what does the autonmic nervous system control
visceral effectors
what are the two divisions of the automonic nervous system
parasympathetic and sympathetic
describe the meaning of duel innervation
parasympathetic and sympathetic innrcate all body systems
what part of the spinal cord do the sympathetic nerves originate
thoracolumbar (t1-L2)
what regions of the spinal cord do the parasympathetic nerves originate?
sacral region and brainstem
describe the anatomy of the sympathetic nervous system
short preganglionic–> ganglia–> ling postganglionic –> effector organ
waht are the two exceptions for the general rule of anatomy of the sympathetic nervous system
collateral ganglia
suprarneal medulla
describe the anatomy of the parasympathetic nervous system
long preganglionic–> short postganglionic–> ganglia–> effector organ
where do preganglionic nerves originate in the parasympathetic nervous system
brain stem or sacral spinal cord
what cranial nerves are involved in the parasympathetic nervous system
III, VII, IX, and X
with respect to the sacral spinal nerves of the parasympathetic nervous system, what do the postganglionic nerve fibers innervate
visceral organs in the ingerior portion of the abdominopelvic cavity
what are the primary neurotransmitters involved in the automonic nervous system
acetylcholine, norpinephrine and epinephrin
describe which brances release acetylcholine versus corepinephrine in the sympathetic and parasympathetic nervous systems
1.acetylcholine–>
SYMPATHETIC: preganglionic & PARASYMPATHETIC: preganglionic and postganglionic
2.norepinephrine–>
SYMPATHETIC: postganglionic
what areas of the brain regulate autonomic function
hypothalamus, pons, medulla oblongata
give a summary of the characteristics of parasympathetic activity
rest & digest, decreased HR, BP, and metabolic rate; increased digestion and gastrointestinal activities
characteristics of sympathetic activity
fight or flight, increased HR, BP, and alertness; decreased gastrointestinal and urinary function; pupils dilate
describe what is means by tonic activity at rest
both branches are active, but at rest, parasympathetic nervous system dominates
what are the four ways in which cells can communicate
direct communication
paracrine communication
synaptic communication
endocrine communication
describe the direct communication between cells
- Exchange of ions and molecules between adjacent cells across gap junctions (cell to cell adhesion molecules)
- Occurs between two cells that are the same type
- Highly specialized and extremely fast
- Found a lot in brain and heart
describe the communication that occurs when paracrines are involved
- Chemical signals are secreted and travel a short distance to a nearby cell
- Information is transferred between different cells of a single tissue type
- Most common form of intercellular communication
describe synaptic communication
- Chemical signals (neurotransmitters) are released by a neuron into a synapse
- Target cell (postsynaptic cell) can be any type of cell
describe endocrine communication
- Endocrine cells release chemicals (hormones) into bloodstream
- Alters metabolic activities of multiple tissues and organs simultaneously
- Endocrine communication involves a hormone and it’s target cell
what are the three ways in which hormones can alter the activity of a target cell
- Stimulate synthesis of enzymes or structural proteins that are not already in the target cell
- Increase or decrease the rate of synthesis of certain enzymes or proteins
- Can turn an existing enzyme or membrane channel “on” or “off”
what are the three types of hormones based on structure alone
amino acid
peptide
what are the two ways in which hormones are transported through the body
freely
bound to transport proteins
describe the characteristics of free hormones
short lived, broken down by enzymes, taken in by liver
describe the characteristics of hormones that are bound to transport proteins
stay in blood longer (are on reserve)
what are the two types of responses that mediate the transport of chemicals in the body
intracellular
membrane bound receptors
describe the characteristics of intracellular mediated responses
used by lipid soluble hormones
what type of hormones use membrane bound receptors
not lipid soluble
what are G proteins
regulatory protein associated with plasma membrane
map out the second messenger system involving cAMP
messenger->activates G protein->alpha G protein activates adenylate cyclase->produces conversion of ATP to cAMP->activates protein cynase->phosphorlate protein-> cell response
Map out the second messenger system that uses PLC as its amplifier enzyme
messenger attachs to membrance->activates G protein->alpha G protein detaches and acivates PLC-> generates DAG and IP3->
- DAG activates protein kinase C-> phosphoralate proteins to make response in target cell
- IP3 moves into cytosol->binds to receptor on the ER-> opens channels and allows Ca into cytosol to cause a response (contraction, secretion)
five types of second messengers
cAMP IP3 cGMP DAG calcium ions (only ions that can be)
what are the two types of endocrine organs in the body and what is the difference between the two
- primary: only hormone secretion
- secondary: secrete hormones but are known for different function (eg heart)
what second messenger does the pituitary glad use
cAMP
what connects the hypothalamus to the pituitary gland
infindibulum
what are the hormones secreted by the posterior pituitary galnd and what is their function
- antidiuretic hormone: water balance and osmolarity of kidney
- oxytocin: uterine contraction and milk