10-25-13 (BIO 181) Flashcards
entry of sound waves
outer ear
amplification of sound waves (ENDS AT TYMPANIC MEMBRANE)
- Middle ear
transduction of sound energy
- Inner ear
- Sound travels in the form of
mechanical waves
- Amplitude of waves
- Measured in Decibels (dB)
- Lowest detectable range = 0 dB
- Painful damage to the ear = 140 dB
- Normal speech = 60 dB
- Loudness
- Frequency of waves
- Measured in Hertz (Hz)
- Normal human range = 20 to 20000 Hz
• Pitch
- Sound waves hit ____ membrane and causes it to vibrate
* Sound waves must then must be amplified
tympanic
- Vibration of tympanic membrane causes movement of ___ (bones) of the middle ear
- This is the first level of amplification
ossicles
- Movement of ossicles causes movement of ____ _____
* Second level of amplification
oval window
• Conversion of sound energy to action potentials occurs in cochlea of inner ear
TRANSDUCTION
- Cochlea is separated from the middle ear via the ____ and ____ ___
Oval and Round windows
- Cochlea is a closed structure that is composed of THREE fluid filled compartements
- Scala Vestibuli (perilymph)
- Scala Tympani (perilymph)
- Scala Media (endolymph)
endolymph has a high concentration of
potassium ions
- When sound waves hit the oval window, oval window vibrates
- This causes waves to occur in the perilymph of scala vestibuli
- Waves then travel to the scala tympani
- This causes movement of the round window
- Organ of Corti is located within the Scala Media of the cochlea (at the top of Basilar membrane)
- Contains HAIR CELLS
sound
- Hair cells act as the the Receptor cells for sound
- Contain Stereocilia
• Have tips that are embedded in tectorial membrane
• Oriented short to tall - Surrounded by endolymph
- Stereocilia of hair cells are connected by protein bridges
sound
- Mechanical stress (from sound) moves protein bridges and causes opening or closing of mechanically gated___ ____
K+ channels
- Bend to tall stereocilia, channels open → ________ (potassium enters cell)
- Bend to short stereocilia,channels close → _______ (potassium does not leak into cell)
depolarization; hyperpolarization
- Hair cells synapse on afferent axons of CN VIII
• Axons make up cochlear nerve
• One hair cell per one cochlear nerve fiber - Cochlear nerve enters brainstem
• Synapses with second-order neuron - Second-order neuron project onto the medial geniculate nucleus of thalamus
- Synapse on third-order neuron
- Third-order neuron projects onto auditory cortex
• Cranial Nerve VIII = Vestibulocochlear Nerve - Vestibular nerve branch for equilibrium
- Cochlear nerve branch for hearing
Neural Pathways for Sound
- Olfactory receptor cells are one of a few neurons in the human body that are replaced continuously
- Receptor cells have cilia that project into the mucus that lines the nasal cavity
- Mucus contains Olfactory binding proteins which transport odorants to the receptor cells
Special Senses - Olfaction
Olfactory Receptor Cells
- Air-borne chemicals must first dissolve in mucus
- The Olfactory binding proteins deliver olfactants (chemicals) to receptor cells
• Upon binding to the receptor, odorants trigger the production of cAMP (via the activation of a G protein)
• This ultimately causes a depolarization of the receptor cells - Once depolarized, receptors send their axons through the Cribriform plate (base of skull with holes) and towards the brain
olfactory signal transduction
- Axons of receptor cells comprise CN I, the olfactory nerve
- Olfactory nerve then relays the information directly to the Olfactory Bulb in the brain
- Axons leaving olfactory bulb travel along olfactory tract to reach olfactory cortex
- Olfaction is the only sensory modality that has direct access to the cerebral cortex and DOES NOT have to go through the thalamus before reaching the cerebrum
Neural Pathway for Olfaction
• Gustation provides information about taste and depends on chemicals in food (and liquids) that bind to ______
chemoreceptors
- Taste receptors (or gustatory receptors) are distributed on tongue and portions of pharynx and larynx
- Clustered into ___ ____
taste buds
- Located within epithelial projections (lingual papillae) on the superior surface of tongue
taste buds
lingual papillae contain 100 taste buds each
• Circumvallate papillae: