CH 14: 9-27-13 (BIO181) Flashcards
• The brain consists of six regions
- Cerebrum
- Cerebellum
- Diencephalon
- Brainstem – 3 parts
- Mesencephalon
- Pons
- Medulla oblongata
- Largest part of brain
- Controls higher mental functions
- Divided into left and right cerebral hemispheres
- Contains an outer surface layer of gray matter (neural cortex)
cerebrum (cortex)
- Folded surface increases surface area
- Elevated ridges (gyri)
- Shallow depressions (sulci)
- Deep grooves (fissures)
• Neural cortex (cerebral cortex)
- Second largest part of brain
- Coordinates repetitive body movements
- Two hemispheres
- Covered with cerebellar cortex
cerebellum
- Located under cerebrum and cerebellum
- Links cerebrum with brain stem
- Two divisions (thalamus and hypothalamus)
• Diencephalon
• Relays and processes sensory information in diencephalon
thalamus
• Neural AND endocrine functions
– Hormone production
– Emotion
– Autonomic function
hypothalamus
- Major endocrine gland
- Connected to hypothalamus via infundibulum (stalk)
- Acts as the interface between the nervous and the endocrine systems
• Pituitary gland (anterior and posterior)
brain stem 3 parts
mesencephalon, pons, medulla oblongata
- Also called midbrain
- Processes sight, sound, and associated reflexes
- Maintains consciousness
- THIS IS THE SENSORY-MOTOR INTEGRATOR!
• Mesencephalon
- Connects cerebellum to brain stem
* Is involved in somatic and visceral motor control
• Pons
• Connects brain to spinal cord
• Relays sensory information
• Regulates autonomic functions:
– heart rate, blood pressure, and digestion
• Medulla oblongata
• The CNS begins as a hollow
neural tube
• Throughout development, the_____ _____ (region that will become brain) expands
cephalic region
– Prosencephalon Will become
forebrain
mesencephalon will become
midbrain
rhombencephalon will become
hindbrain
• Prosencephalon and Rhombencephalon further differentiate into
secondary brain regions
• Prosencephalon differentiates into the _____ (which becomes cortex) and _____
Telencephalon; Diencephalon
mesencephalon changes the ____ during growth
least
• During development, the Neural tube encloses a _____
neurocoel (a fluid filled internal cavity)
• This Neurocoel expands to form _____ lined with ependymal cells
chambers (ventricles)
• Eventually, each cerebral hemisphere contains one large
Lateral ventricle
- Ventricle of the diencephalon
* Lateral ventricles communicate with third ventricle via the interventricular foramen
• Third ventricle
- Extends into medulla oblongata
* Becomes continuous with central canal of the spinal cord
• Fourth ventricle
- Bones of the cranium
- Cranial meninges
- Cerebrospinal fluid
physical protection of the brain
blood brain barrier
biochemical isolation of brain
- Protect the brain from cranial trauma
* Have three layers:
cranial meninges
• Inner fibrous layer (meningeal layer)
• Outer fibrous layer (endosteal layer)
• Venous sinuses are between the two layers
– Contain fluids and blood vessels
– Receives venous blood and delivers it to the jugular veins
dura mater of brain
- Covers brain
- Contacts epithelial layer of dura mater
- Subarachnoid space: between arachnoid mater and pia mater
arachnoid mater of brain
• Attached to brain surface by astrocytes
pia mater of brain
- Surrounds all exposed surfaces of CNS
- Functions of CSF
- Cushions neural structures
- Supports brain
- Transports nutrients, chemical messengers, and waste products
CFS
• Consists of specialized ependymal cells and capillaries:
– secrete CSF into ventricles
– remove waste products from CSF
– adjust composition of CSF
• Formation of CSF starts in the Choroid plexus
- From choroid plexus
- Through ventricles
- To central canal of spinal cord
- Into subarachnoid space around the brain and spinal cord
circulation of CSF
• extend through dura mater to superior sagittal sinus
• Clusters of these villi are called Arachnoid granulations
– Function in absorbing CSF into venous ciculation
• Subarachnoid space contains Arachnoid villi:
- Isolates CNS neural tissue from general circulation
- Formed by network of tight junctions between endothelial cells of CNS
- Allows ONLY lipid-soluble compounds (O2, CO2), steroids, and prostaglandins to diffuse into interstitial fluid of brain and spinal cord
- Astrocytes control blood–brain barrier by releasing chemicals that control the permeability of endothelium
• Blood-Brain Barrier
- Meninges stabilize brain in cranial cavity
- Cerebrospinal fluid cushions and protects against sudden movement
- CSF provides nutrients and removes wastes
- Blood–brain barrier and blood–CSF barrier
- Selectively isolate brain from chemicals in blood that might disrupt neural function
Brain Protection and Support Summary