The Control of Gene Expression: Using Genome Projects

Question 1

What is a genome?

Answer 1

• Complete set of genes of a cell

Question 2

What are the uses of determining the genome of simpler organisms?

Answer 2

• Allows the sequences of the proteins in the proteome of the organism to be determined
• This can be used to identify potential antigens for vaccine production

Question 3

What is a proteome?

Answer 3

• Entire set of proteins that a cell can produce

Question 4

Why is determining the genome of simpler organisms easier than in more complex organisms?

Answer 4

• Simple organisms e.g bacteria don’t have much non-coding DNA so genome can be easily translated into proteome
• Complex organisms have large sections of non-coding DNA: regulatory genes (transcription factors), introns, base repeats

Question 5

How effective are sequencing methods in genome projects?

Answer 5

• Sequencing methods are continuously updated and have become automated