The Cell Cycle: Chp 12 Flashcards

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1
Q

cell cycle

A

the life of a cell from the time it is first formed from a dividing parent cell until its own division into two cells

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2
Q

genome

A

the cells genetic information

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3
Q

somatic cells

A

all body cells except gametes (they have 46 chromosomes)

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4
Q

mitosis

A

the process by which somatic cells divide, forming daughter cells that contain the same chromosome number as the parent cell

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5
Q

gametes

A

sperm and egg cells (haploid). they go through meiosis

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6
Q

sister chromatids

A

there are 2 and they are each of the duplicated chromosomes when they are attached

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7
Q

centromere

A

where the two sister chromatids attach

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8
Q

mitosis

A

the division of the cell’s nucleus (1 cell turns to 2)

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9
Q

cytokinesis

A

the division of the cells cytoplasm

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10
Q

interphase

A

90% of the cell cycle that consists of G1, S, and G2 phases

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11
Q

G1 phase

A

first portion of interphase. the cell grows while carrying out cell functions unique to its cell type

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12
Q

S phase

A

second portion of interphase. the cell continues to carry out its unique functions but does one other important process-it duplicates its chromosomes meaning it makes a copy of DNA that makses up the cells chromosomes

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13
Q

G2 phase

A

the last portion of interphase. the gap after the chromosomes have been duplicated and just before mitosis

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14
Q

prophase

A

1: the chromatin becomes more tightly coiled into discrete chromosomes
2: the nucleoli disappears
3: the mitotic spindle begins to form in the cytoplasm

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15
Q

premetaphase

A

1: the nuclear envelope begins to fragment, allowing the microtubules to attach ot the chromosomes
2: the two chromatids of each chromosome are held together by protein kinetochores in the centromere region
3: the microtubules will attach to the kinetochores

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16
Q

metaphase

A

1: the microtubules move the chromosomes to the metaphase plate at the equator of the cell. the microtubule complex is referred to as the spindle.
2: the centrioles have migrated to opposite poles in the cell, riding along on the developing spindle

17
Q

anaphase

A

1: sister chromatids begin to separate, pulled apart by motor molecules interacting with kinetochore microtubules
2: the cell elongates, as the nonkinetochore microtubules ratchet apart, again with the help of motor molecules
3: by the end of anaphase, the opposite ends of the cell both contain complete and equal sets of chromosomes

18
Q

telophase

A

1: the nuclear envelopes re-form around the sets of chromosomes located at opposite ends of the cell
2: the chromatin fiber of the chromosomes becomes less condensed
3: cytokinsesis begins, which is where the cytoplasm of the cell is divided. In animal cells, a cleavage furrow forms and divides. in a plant cell, a cell plate forms that divides the cytoplasm
4: prokaryotes replicate their genome by binary fission rather than mitosis

19
Q

cell cycle control system

A

this controls the steps of the cycle. It moves the cell through stages by a series of checkpoints where signals tell the cell to either continue dividing or stop.

20
Q

The major cell checkpoints

A

G1 phase checkpoint, G2 phase checkpoint, and M phase checkpoint

21
Q

G1 phase checkpoint

A

seems the most important. if the cell gets the go-ahead signal, it usually completes the whole cell cycle and divides. If it does not receive the signal, it enters a nondividing phase called the G0 phase

22
Q

kinases

A

the protein enzymes that control the cell cycle. they exist in the cells at all times but are active only when they are connected to cyclin protein; thus, they are called cyclin-dependent kinases

23
Q

denisty dependent inhibition

A

the phenomenon in which crowded cells stop dividing

24
Q

anchorage dependency

A

normal cells must be attached to a substrate tum, like the extracellular matrix of a tissue, to divide

25
Q

transformation

A

the process that converts a normal cell to a cancer cell

26
Q

tumor

A

a mass of abnormal cells wihtin otherwise normal tissue

27
Q

benign tumor

A

if the abnormal cells remain at the original site

28
Q

malignant tumor

A

becomes invasive enough to impair the functions of one or more organs. it is also said that it is cancer

29
Q

metastasis

A

occurs when cells separate from a malignant tumor and enter blood or lymph vessels and travel to other parts of the body