the cell cycle Flashcards
what are the 2 different types of cells based on
chromosome content
2 cell types?
gametes
somatic cells
gametes
23 different chromosomes=haploid (n) includes ova (eggs) and sperm
somatic cells
-includes all cells of body except cell undergoing/resulting from meiosis
-46 chromosomes = diploid (2n)
-23 homologous pairs
each somatic cell contains 23 different chromosome pairs (23 chromosomes from mom (ovum) pairs with 23 chromosomes from dad (sperm) = 46 chromosomes (diploid = 2n)
-chromosomes and chromosome pairs are numbered 1-23:
a) 1 to 22 = autosomal chromosomes (autosomes)
-contain genes for somatic characteristics
eg. hair and eye colour, height
-each autosomal chromosome pair is not identical, but equivalent = homologous chromosomes
b)23 = sex chromosome
-contain genes that determine sex, XX=F and XY=M
-X or Y from Dad
-X from mo
homologous chromosomes
a chromosome pair (1 from each parent) that are identical in length, centromere position, and have genes for the same trait (eye colour) in the same location (locus)
- but may have different versions (alleles) of that gene that code for different version of that trait
eg. blue eyes (chromosome from Dad), brown eyes (chromosome from mom)
gene
a unit of heredity= a region of DNA which contains info for synthesis of proteins
cell cycle
for growth and repair of tissues
- somatic “parent” cell 2n -> 2 genetically identical somatic daughter cells 2n
- 2 stages : interphase and mitotic phase
interphase
- chromosomes present as chromatin
- normal cellular metabolic activities occurring eg. protein synthesis
- G1, S, and G2
G1
- growth, metabolism
- at end of G1, centrosomes replicate
- in some cells that do not divide again once mature (ie. remain in G1)- in these cells it is termed G0 phase
eg. nerve and some muscle cells
S
- chromosome replicate but are still present as chromatin (not individually visible)
- always occurs before division (mitosis and meiosis)
- replicates are called sister chromatids
- attached to each other as an area of DNA called the centromere
- kinetochore proteins (produced during S phase ) attach to each centromere to form the kinetochore (=protein + DNA complex, 1/ chromatid)
kinetochore
site of attachment of spindle microtubules
G2
Growth, metabolism
-production of enzymes and other proteins needed for cell division
mitotic phase
-mitosis= divisions of nuclear material (chromosomes)
-4 phases, but continuous cycles
prophase, metaphase, anaphase, telophase
-cytokinesis= division of cytoplasm
when mitotic phase ends
- mitosis and cytokinesis complete
- daughter cell go into interphase G1
- cycle starts over