the cell cycle Flashcards

1
Q

what are the 2 different types of cells based on

A

chromosome content

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2
Q

2 cell types?

A

gametes

somatic cells

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3
Q

gametes

A
23 different chromosomes=haploid (n)
includes ova (eggs) and sperm
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4
Q

somatic cells

A

-includes all cells of body except cell undergoing/resulting from meiosis
-46 chromosomes = diploid (2n)
-23 homologous pairs
each somatic cell contains 23 different chromosome pairs (23 chromosomes from mom (ovum) pairs with 23 chromosomes from dad (sperm) = 46 chromosomes (diploid = 2n)
-chromosomes and chromosome pairs are numbered 1-23:
a) 1 to 22 = autosomal chromosomes (autosomes)
-contain genes for somatic characteristics
eg. hair and eye colour, height
-each autosomal chromosome pair is not identical, but equivalent = homologous chromosomes
b)23 = sex chromosome
-contain genes that determine sex, XX=F and XY=M
-X or Y from Dad
-X from mo

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5
Q

homologous chromosomes

A

a chromosome pair (1 from each parent) that are identical in length, centromere position, and have genes for the same trait (eye colour) in the same location (locus)

  • but may have different versions (alleles) of that gene that code for different version of that trait
    eg. blue eyes (chromosome from Dad), brown eyes (chromosome from mom)
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6
Q

gene

A

a unit of heredity= a region of DNA which contains info for synthesis of proteins

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7
Q

cell cycle

A

for growth and repair of tissues

  • somatic “parent” cell 2n -> 2 genetically identical somatic daughter cells 2n
  • 2 stages : interphase and mitotic phase
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8
Q

interphase

A
  • chromosomes present as chromatin
  • normal cellular metabolic activities occurring eg. protein synthesis
  • G1, S, and G2
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9
Q

G1

A
  • growth, metabolism
  • at end of G1, centrosomes replicate
  • in some cells that do not divide again once mature (ie. remain in G1)- in these cells it is termed G0 phase
    eg. nerve and some muscle cells
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10
Q

S

A
  • chromosome replicate but are still present as chromatin (not individually visible)
  • always occurs before division (mitosis and meiosis)
  • replicates are called sister chromatids
  • attached to each other as an area of DNA called the centromere
  • kinetochore proteins (produced during S phase ) attach to each centromere to form the kinetochore (=protein + DNA complex, 1/ chromatid)
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11
Q

kinetochore

A

site of attachment of spindle microtubules

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12
Q

G2

A

Growth, metabolism

-production of enzymes and other proteins needed for cell division

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13
Q

mitotic phase

A

-mitosis= divisions of nuclear material (chromosomes)
-4 phases, but continuous cycles
prophase, metaphase, anaphase, telophase
-cytokinesis= division of cytoplasm

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14
Q

when mitotic phase ends

A
  • mitosis and cytokinesis complete
  • daughter cell go into interphase G1
  • cycle starts over
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