Histology (tissues) Flashcards
histology
the study of tissues
tissues
a group of cells with similar structure and function
4 major tissues
epithelial
connective
muscle
nervous
cell junctions
in some tissues
- points of contact b/w adjacent cells- seen in epithelial tissue, some nervous and muscle cells
- formed by cell membrane proteins
types of cell junctions
tight
anchoring
gap
tight junctions
are a partial fusion of specific proteins on the lateral surface of the cell membrane
- form ring-like right seal
- prevents material from passing b/w cells eg. bacteria, proteins, sometimes fluid or ions (depending on the tissue)
anchoring junctions
eg. desmosomes
- protiens that fasten cells to each other and or extracellular material (“rivets” cells together)
Gap junctions
open channels (formed by proteins) through the adjacent cell membranes interconnecting the cytosols of the cells
- allows ions/small molecules to pass from on cell to another
- tissues can then work as a unit:
- important in cardiac and smooth muscle (allows synchronization of contractions)
- also found in epithelial tissue
epithelial tissue
lining tissue
- covers body surface
- lines body/organ cavities
organ cavity
lumen
classification of epithelia
- most subtypes are classified and named according to:
1. number of cell layers sitting on the basement membrane - one layer=simple
- more than one layer = stratified
2. shape of the ells in the apical layer (=layer touching the free surface) - flattened=squamous
- round or cube shaped=cuboidal
- rectangular=columnar
1. simple epithelia
2. stratified epithelia
3. pseudo-stratified epithelia
4. transitional epithelia
5. glandular epithelium
simple epithelia
1 layer
- allow exchange of molecules (gasses, nutrients)- absorption/secretion
- 3 subtypes
simple squamous
1 layer of squished flat cells
eg. lungs
simple cuboidal
1 layer of cube shaped cells
eg. kidneys
simple columnar
1 layer of column shaped tall and thing cells
eg stomach, small intestine
stratified epithelia
> 1 layer
-protective (areas of abrasion)
3 subtypes
stratified squamous
apical cells squished flat
eg. skin
stratified cuboidal
apical cells cube shaped
- rare