The Cardiovascular System Flashcards
What are the 2 types of circulation? What kind of blood does each receive?
- Pulmonary - deoxygenated blood
2. Systemic - oxygenated blood
What valve separates the right atria and the right ventricle?
Tricuspid
What valve separates the left atria and the left ventricle?
Bicuspid
What valve separates the right ventricle and the vasculature?
Pulmonary
What valve separates the left ventricle and the vasculature?
Aortic
What is the FULL blood pathway?
- Right atrium
- Right ventricle
- Pulmonary artery
- Lungs
- Pulmonary vein
- Left atrium
- Left ventricle
- Aorta
- Arteries
- Arterioles
- Capillaries
- Venules
- Veins
- Vanea cavae
- Right atrium
Which side of the heart is more muscular? Why?
The left side because the systemic circulation has a much higher resistance and pressure
What is the pathway of electrical conduction in the heart?
- SA node
- 2 atria contract
- Atrial systole –> atrial kick
- AV node
- Bundle of His
- Purkinje fibers
Where is the SA node?
At the top of the atria
Where is the AV node?
In the middle of the heart above the 2 ventricles
What are cardiac muscle cells connected by? What do these contain?
Intercalated discs
Gap junctions
Through which nerve does the heart receive neural input to slow down?
Vagus nerve
What happens during systole?
Ventricules contract
What happens during diastole?
Atria contract
What is the cardiac output equation?
CO = heart rate . volume of blood per beat
What is the P wave of the EKG?
Just before the atria contract
What is the QRS complex on the EKG?
Just before the ventricles contract
What is the T wave of the EKG?
Ventricular repolarization
What happens during a heart attack or myocardial infarction?
Lack of O2 to heart –> muscle tissue begins to die
How to treat a heart attack or myocardial infarction?
Beta blockers: they block the sympathetic stimulation –> decrease heart rate
What is the S1 sound due to?
AV valves closing
What is the S2 sound due to?
Semilunar valves closing
What are the S3 and S4 sounds due to?
Stiffness of heart or high blood pressure
What is ventricular tachycardia?
Elevated heart rate –> ventricles cannot properly fill up –> drop in systemic blood pressure –> death
What are the 2 types of arteries that contain deoxygenated blood?
Pulmonary and umbilical
What are the 2 types of veins that contain oxygenated blood?
Pulmonary and umbilical
What are varicose veins due to?
Failure of venous valves
What is another name for platelets?
Thrombocytes
What is hemolysis?
destruction of red blood cells
What antigens does the blood type A produce?
A
What antibodies does the blood type A produce?
Anti-B
What antibodies does the blood type O produce?
Anti-A and Anti-B
What antibodies does the blood type AB produce?
None
What antigens does the blood type O produce?
None
What antigens does the blood type B produce?
B
What antigens does the blood type AB produce?
A and B
What antibodies does the blood type B produce?
Anti-A
What blood type can A types donate to?
A, AB
What blood type can B types donate to?
B, AB
What blood type can O types donate to?
All
What blood type can AB types donate to?
AB only
Is the Rh factor dominant or recessive?
Dominant
What is blood pressure measured by?
Sphygmomanometer
What is the role of the atrial natriuretic peptide hormone?
Lower blood pressure
What type of reaction binds and releases O2 on hemoglobin?
Redox
What does the hydrostatic pressure do? What does it depend on?
It pushes fluids out of vessels into the tissues
Depends on blood pressure –> heart beat
What does the oncotic/osmotic pressure do? What does it depend on?
It pulls fluids back into the vessels
Depends on number of particles in the blood
What is the balancing of the osmotic and hydrostatic pressures called?
Starling forces
Describe the coagulation cascade (6 steps)
- Endothelial lining of vessel is damaged
- Collagen and tissue factor are exposed
- Platelets bind to collagen
- Thrombin activates fibrin
- Fibrin stabilizes the platelets binding
- Plasmin breaks down the clot
Which cells are the only blood cells to contain a nucleus?
Leukocytes
What is the enzyme catalyzing the bicarbonate buffer system?
carbonic anhydrase
What is the vascular structure creating the most resistance to blood flow?
Arterioles
What is albumin?
The main protein in plasma
Why is there more blood in the pulmonary circulatory system?
Because the veins lack smooth muscles and can stretch
During pregnancy, can the two bloods touch each other?
Yes, a very small amount
Is hemoglobin a homotetradimer or a heterotetradimer? Why?
Hetero, because each hemoglobin has 2 subunits